Based on the long-running TV mystery series, Murder, She Wrote puts players in the shoes of novelist/sleuth Jessica Fletcher as she tries to uncover clues to a series of troubling murders. The game takes place primarily in the sleepy Maine town of Cabot Cove, but five standalone mysteries send gamers to a variety of different locales, including Vermont and England. Along the way, players must search cluttered crime scenes for hidden objects, interview witnesses, analyze evidence, solve puzzles, and seek advice from series mainstays Dr. Seth Hazlitt and Sheriff Mort Metzger.