Table of Content
List of Contributors, vii Introduction, xiii 1 Central Nervous System Manifestations of Chromosomal Change, 1 Joseph R. Siebert 2 Neural Tube Defects, 13 Andrew J. Copp and Brian N. Harding 3 Midline Patterning Defects, 29 Edwin S. Monuki and Jeffrey A. Golden 4 Microcephaly, 41 Sandrine Passemard, Annie Laquerriere, ' Nathalie Journiac, and Pierre Gressens 5 Hemimegalencephaly and Dysplastic Megalencephaly, 55 Ghayda Mirzaa, Achira Roy, William B. Dobyns, Kathleen Millen, and Robert F. Hevner 6 Lissencephaly, Type I, 63 Jeffrey A. Golden 7 Lissencephaly, Type II (Cobblestone Lissencephaly), 75 Jeffrey A. Golden 8 Polymicrogyria, 85 Jeffrey A. Golden 9 Cerebral Heterotopia, 91 Edwin S. Monuki and Keith L. Ligon 10 Hippocampal Sclerosis, Granule Cell Dispersion, and Cortical Dysplasia, 101 Maria Thom 11 Tuberous Sclerosis Complex, 117 Shino D. Magaki and Harry V. Vinters 12 Chiari Malformations, 133 Homa Adle-Biassette and Jeffrey A. Golden 13 Dandy-Walker Malformation, Mega Cisterna Magna, and Blake''s Pouch Cyst, 141 Robert F. Hevner, Kathleen Millen, and William B. Dobyns 14 Joubert Syndrome, 151 Robert F. Hevner, William B. Dobyns, and Enza Maria Valente 15 Cerebellar Heterotopia and Dysplasia, 159 Marie Rivera-Zengotita and Anthony T. Yachnis 16 Brainstem Malformations, 167 Brian N. Harding 17 Spinal Cord Lesions, 179 Annie Laquerriere and Florent Marguet 18 Hydrocephalus, 187 Homa Adle-Biassette 19 Antenatal Disruptive Lesions, 199 Brian N. Harding 20 Hemorrhagic Lesions, 203 Marc R. Del Bigio 21 White Matter Lesions in the Perinatal Period, 213 Robin L. Haynes and Rebecca D. Folkerth 22 Gray Matter Lesions, 229 Marc R. Del Bigio 23 Pediatric Head Injury, 241 Colin Smith, Thomas S. Jacques, and R. Ross Reichard 24 Pediatric Vascular Malformations, 251 Shino D. Magaki, Randy Tashjian, and Harry V. Vinters 25 Sudden Infant Death Syndrome, 269 Hannah C. Kinney, Marco M. Hefti, Richard D. Goldstein, and Robin L. Haynes 26 Kernicterus, 281 Mariarita Santi and Lucy B. Rorke 27 Lesions Induced by Toxins, 285 Mariarita Santi, Lucy B. Rorke, and Catherine Keohane 28 Disorders of Carbohydrate Metabolism, 293 Josefine Radke, Carsten G. Bonnemann, ¨ Werner Stenzel, and Hans-H. Goebel 29 Sphingolipidoses and Related Disorders, 313 Annie Laquerriere, Soumeya Bekri, Kinoko Suzuki, and Brian N. Harding 30 The Neuronal Ceroid Lipofuscinoses, 369 Josefine Radke, Krystina E. Wisniewski, Werner Stenzel, and Hans-H. Goebel 31 Peroxisomal Disorders, 381 Phyllis L. Faust 32 Mitochondrial Disorders, 393 Anders Oldfors and Brian N. Harding 33 Disorders of Amino Acid Metabolism and Canavan Disease, 403 Dimitri P. Agamanolis 34 Pelizaeus-Merzbacher Disease, 417 Brian N. Harding 35 Cockayne Syndrome, 427 Karen M. Weidenheim and P. J. Brooks 36 Vanishing White Matter Disease, 437 Marianna Bugiani, James M. Powers, and Marjo S. van der Knaap 37 Alexander Disease, 447 James E. Goldman and Mel B. Feany 38 Neuroaxonal Dystrophy/Neurodegeneration with Brain Iron Accumulation, 455 Abi Li, Sarah Wiethoff, Charles Arber, Henry Houlden, Tamas Revesz, and Janice L. Holton 39 Spinal Muscular Atrophy, 469 Brian N. Harding 40 Autism Spectrum Disorders, 477 Matthew P. Anderson 41 Intrauterine Infections, 497 Catherine Keohane and Homa Adle-Biassette 42 Perinatal and Postnatal Infections, 511 Catherine Keohane 43 Rasmussen Encephalitis, 531 Harry V. Vinters, Shino D. Magaki, and Geoffrey C. Owens Index, 537
