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Sphingolipid Biology by Y. Igarashi (2014, Trade Paperback)

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Sphingolipid Biology by Y. Hirabayashi, Y. Igarashi, A.H. Jr. Author Y. Hirabayashi, Y. Igarashi, A.H. Jr. Title Sphingolipid Biology. Format Paperback.

About this product

Product Information

Sphingolipids are fundamental to the structures of cell membranes, lipoproteins, and the stratum cornea of the skin. Many complex sphingolipids as well as simpler sphingoid bases and derivatives are highly bioactive as extra- and intracellular regulators of growth, differentiation, migration, survival, senescence, and numerous cellular responses to stress. This book provides many examples of exciting new developments in sphingolipid biology/sphingolipidology that are changing our understanding of how multicellular organisms grow, develop, function, age, and die. Key areas addressed include sphingolipid biosynthesis, transport and membrane organization/lipid rafts; genetic approaches to understanding the roles of membrane sphingolipid biosynthesis; sphingolipid metabolism, specific G protein-coupled receptors (GPCRs), and signal transduction; and sphingolipid-associated disease and drug development.

Product Identifiers

Publisher
Springer Japan
ISBN-10
4431546669
ISBN-13
9784431546665
eBay Product ID (ePID)
239981583

Product Key Features

Author
Y. Igarashi
Publication Name
Sphingolipid Biology
Format
Trade Paperback
Language
English
Publication Year
2014
Type
Textbook
Number of Pages
Xxv, 531 Pages

Dimensions

Item Length
9.3in
Item Width
6.1in
Item Weight
29.9 Oz

Additional Product Features

Number of Volumes
1 Vol.
Lc Classification Number
Qh573-671
Table of Content
Part 1: Overview.- Sphingolipids Synthesis, Transport and Cellular Signaling Serine Palmitoyltransferase.- Part 2: Biosynthesis, Transport of Sphingolipids.- Serine Palmitoyltransferase.- Ceramide Synthase.- Dihydroceramide: Sphinganine D 4-Desaturase and C4-Hydroxylase.- Metabolizing Enzymes Such As Sphingomyelin Synthase Induce Cell Death by Increasing Ceramide Content.- Glucosylceramide and Galactosylceramide Synthase.- Synthesis, Metabolism, and Trans-Bilayer Movement of Long-Chain Base.- Molecular Mechanism of Ceramide Trafficking from the Endoplasmic Reticulum to the Golgi Apparatus in Mammalian Cells.- Sphingolipid Trafficking.- Current Perspectives on Saccharomyces cerevisiae Sphingolipids.- Part 3: Generation and Degradation of Sphingolipid Signaling Molecules.- Generation of Signaling Molecules by de novo Sphingolipid Synthesis.- Overview of Acid and Neutral Sphingomyelinases in Cell Signaling.- Neutral Ceramidase as an Integral Modulator for the Generation of S1P and S1P-Mediated Signaling.- Activation of Sphingosine Kinase 1.- Ceramide 1-Phosphate.- Sphingosine-1-Phosphate Lyase.- Part 4: Membrane Domain and Biological Function.- Close Interrelationship of Sphingomyelinase and Caveolin in Triton X-100-Insoluble Membrane Microdomains.- Roles of Membrane Domains in the Signaling Pathway for B Cell Survival.- The Role of Lipid Rafts in Axon Growth and Guidance.- Sphingolipids and Multidrug Resistance of Cancer Cells.- Part 5: Membrane Lipid Domain and Human Pathobiology.- A New Pathological Feature of Insulin Resistance and Type 2 Diadetes: Involvement of Ganglioside GM3 and Membrane Microdomains.- Neuronal Cell Death in Glycosphingolipidoses.- Endocytic Trafficking of Glycosphingolipids in Sphingolipidoses.- Ganglioside and Alzheimer's
Copyright Date
2006
Target Audience
Scholarly & Professional
Topic
Life Sciences / Molecular Biology, Life Sciences / Biochemistry
Dewey Decimal
572.57
Illustrated
Yes
Genre
Science

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Picture 1 of 1

Sphingolipid Biology by Y. Igarashi (2014, Trade Paperback)

About this product

Product Information

Product Identifiers

Product Key Features

Dimensions

Additional Product Features

Best Selling in Textbooks

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Designing Data-Intensive Applications : The Big Ideas Behind Reliable, Scalable, and Maintainable Systems by Martin Kleppmann (2017, Trade Paperback)

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