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Serotonin Transporter Gene and Personality by Xenia Gonda (2010, Trade Paperback)

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About this product

Product Identifiers

PublisherAV Akademikerverlag Gmbh & Co. KG

ISBN-103639297059

ISBN-139783639297058

eBay Product ID (ePID)116929567

Product Key Features

Book TitleSerotonin Transporter Gene and Personality

Number of Pages96 Pages

LanguageEnglish

Publication Year2010

TopicLife Sciences / Genetics & Genomics

GenreScience

AuthorXenia Gonda

FormatTrade Paperback

Dimensions

Item Height0.2 in

Item Weight5.5 Oz

Item Length9 in

Item Width6 in

Additional Product Features

TitleLeadingThe

SynopsisWe investigated the association of depression, anxiety and affective temperaments with 5-HTTLPR. People carrying the s allele were more prone to anxiety, depression and more likely to carry affective temperaments incorporating a depressive component. From the aspect of gene-environment interactions, our results show that the presence of dominant affective temperaments and neuroticism- related traits confers increased vulnerability to chronic stress which plays a crucial role in the development of depression. Our findings open the potential to identify people with temperamental inclination to mood instability with the joint use of measures of behavioural endophenotypes and molecular genetic markers. Our findings bring psychiatric genetics closer to the aim of delineating risk profiles for affective disorders in more precise quantitative measures and thus point to the possibility of preventive psychological and biological therapies. This emphasises the need for research to delineate the genetic background of traits observable in the healthy population as endophenotypes related to neuropsychiatric disorders.