CURRENTLY SOLD OUT

Pharmacological Management of Crohn's Disease: Future Research Needs: Future Research Needs Paper Number 26 by U S Department of Healt Human Services, Agency for Healthcare Resea And Quality (Paperback / softback, 2014)

About this product

Product Information

Crohn's disease is characterized by chronic inflammation that can occur anywhere in the gastrointestinal tract, but most often affects the small bowel and colon. Typical symptoms include abdominal pain, chronic diarrhea, and gastrointestinal bleeding. Crohn's disease affects between 400,000 and 600,000 North Americans. Ten percent of Crohn's disease patients are children under the age of 17 years. The clinical management of Crohn's disease is complicated. Practice guidelines for Crohn's disease recommend that clinicians take into account the disease location, severity, complications, and extra-intestinal manifestations when choosing a treatment strategy. However, universal treatment strategy exists. The lack of consensus about the best treatment strategy can result in confusion and frustration for the Crohn's disease patient as well as practitioners who treat Crohn's disease patients. Medications are the preferred treatment for Crohn's disease with surgical interventions reserved for complications of disease or evidence of dysplasia. Medical therapy in Crohn's disease targets intestinal inflammation with the intent of altering the natural history of the disease. Corticosteroids and amisalicylates such as sulfasalazine have been used since the 1950s. Immumodulators (6-mercaptopurine, azathioprine, and methotrexate) have been used for the treatment of Crohn's disease since the 1970s, although use of these medications was t routine until the 1990s. The first biologic tumor necrosis factor (TNF)-alpha inhibitor, infliximab, was approved by the Food and Drug Administration (FDA) for the treatment of Crohn's disease in adults in 1998. The FDA-approved moclonal antibodies against TNF-alpha inhibitor also include adalimumab and certolizumab pegol. Ather biologic agents used for the treatment of Crohn's disease include natalizumab, a moclonal antibody against cellular adhesion molecule that is FDA-approved for Crohn's disease in adults. Our recent systematic review addressed several Key Questions in the management of Crohn's disease. In that review, we identified several important gaps in the Evidence. We used the population, intervention, comparison, outcome, timing, setting (PICOTS) framework to identify gaps from the evidence in relationship to the populations, interventions, comparisons, outcomes, timing, and settings relevant to treatments for Crohn's disease. Several gaps related to the target population (children, n-white, and risk stratification based on patient characteristics). Other gaps related to interventions and comparisons of interest (step up versus top down treatment and head to head comparisons within and between treatment classes), outcomes of interest (mucosal healing, and patient-reported symptoms), or a timing issue (remission beyond 2 years). The objective of this report is to identify and prioritize existing gaps in the synthesized literature pertaining to pharmacological induction and maintenance of remission for patients with Crohn's disease by engaging stakeholders using a modified Delphi method.

Product Identifiers

Publisher
CreateSpace
ISBN-10
1499519931
ISBN-13
9781499519938
eBay Product ID (ePID)
220796318

Product Key Features

Author
Agency for Healthcare Resea and Quality, US Department of Healt Human Services
Format
Paperback / Softback, Trade Paperback (US) ,Unsewn / Adhesive Bound
Language
English
Subject
Medicine: General
Type
Textbook

Additional Product Features

Content Note
Black & White Illustrations
Date of Publication
11/05/2014
Country of Publication
United States

Best Selling in Textbooks

Current slide {CURRENT_SLIDE} of {TOTAL_SLIDES}- Best Selling in Textbooks

Desk Reference to the Diagnostic Criteria from DSM-5-TR by American Psychiatric Association (2022, Trade Paperback)
5.0 out of 5 stars based on 6 product ratings
$12.19 New
---- Used
Self Heal by Design : The Role of Micro-organisms for Health by Barbara O'Neill (2018, Trade Paperback)
5.0 out of 5 stars based on 14 product ratings
$33.00 New
$32.00 Used
Diagnostic and Statistical Manual of Mental Disorders DSM-5-TR by American Psychiatric Association (2022, Trade Paperback)
4.6 out of 5 stars based on 15 product ratings
$34.89 New
$34.00 Used
PMBOK® Guide Ser.: Guide to the Project Management Body of Knowledge (PMBOK Guide) and the Standard for Project Management by Project Management Institute (2021, Trade Paperback)
4.9 out of 5 stars based on 7 product ratings
$18.69 New
$13.00 Used
Cognitive Behavior Therapy : Basics and Beyond by Judith S. Beck (2020, Hardcover)
5.0 out of 5 stars based on 4 product ratings
$18.95 New
$17.66 Used
Research Design : Qualitative, Quantitative, and Mixed Methods Approaches by J. David Creswell and John W. Creswell (2022, Trade Paperback)
4.0 out of 5 stars based on 4 product ratings
$19.00 New
$5.27 Used
NFPA 70® Handbook with Tabs : 2023 Edition by National Fire Protection Association (NFPA) (2022, Hardcover)
No ratings or reviews yet
$59.50 New
---- Used

Save on Textbooks

Current slide {CURRENT_SLIDE} of {TOTAL_SLIDES}- Save on Textbooks

Diagnostic and Statistical Manual of Mental Disorders DSM-5-TR w/ PAGE TABLE
$25.00
Trending at $39.99
PMBOK A Guide to the Project Management Body of Knowledge 7th edition (Pb) 📋
$17.99
Trending at $31.31
usa stock Cognitive Behavior Therapy : Basics and Beyond by Judith S. Beck(2020)
$19.90
Trending at $20.80
NEW NFPA 70® NEC Handbook with Index Tabs : 2023 Edition by NFPA USA
$59.50
Trending at $67.45
Designing Data-Intensive Applications : The Big Ideas Behind Reliable Brand New
$15.00
Trending at $18.95
Diagnostic & Statistical Manual of Mental Disorders: DSM-5-TR(Hardcover) Fast...
$41.45
Trending at $43.95

Shop by category

Pharmacological Management of Crohn's Disease: Future Research Needs: Future Research Needs Paper Number 26 by U S Department of Healt Human Services, Agency for Healthcare Resea And Quality (Paperback / softback, 2014)

About this product

Product Information

Product Identifiers

Product Key Features

Additional Product Features

Best Selling in Textbooks

Desk Reference to the Diagnostic Criteria from DSM-5-TR by American Psychiatric Association (2022, Trade Paperback)

Self Heal by Design : The Role of Micro-organisms for Health by Barbara O'Neill (2018, Trade Paperback)

Diagnostic and Statistical Manual of Mental Disorders DSM-5-TR by American Psychiatric Association (2022, Trade Paperback)

PMBOK® Guide Ser.: Guide to the Project Management Body of Knowledge (PMBOK Guide) and the Standard for Project Management by Project Management Institute (2021, Trade Paperback)

Cognitive Behavior Therapy : Basics and Beyond by Judith S. Beck (2020, Hardcover)

Research Design : Qualitative, Quantitative, and Mixed Methods Approaches by J. David Creswell and John W. Creswell (2022, Trade Paperback)

NFPA 70® Handbook with Tabs : 2023 Edition by National Fire Protection Association (NFPA) (2022, Hardcover)

Save on Textbooks

Diagnostic and Statistical Manual of Mental Disorders DSM-5-TR w/ PAGE TABLE

PMBOK A Guide to the Project Management Body of Knowledge 7th edition (Pb) 📋

usa stock Cognitive Behavior Therapy : Basics and Beyond by Judith S. Beck(2020)

NEW NFPA 70® NEC Handbook with Index Tabs : 2023 Edition by NFPA USA

Designing Data-Intensive Applications : The Big Ideas Behind Reliable Brand New

Diagnostic & Statistical Manual of Mental Disorders: DSM-5-TR(Hardcover) Fast...

You may also like

Nonfiction Diseases Paperbacks Books

Future Publishing Magazines

Pharmacology Nonfiction Paperbacks Books

Future Publishing Computers Magazines

Future Publishing Magazines in English

Nonfiction Futurism Fiction & Nonfiction Books