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Estimation of Dorzolamide and Timolol in Eye Drops by a RP-HPLC Method by Ravi Wanare (Paperback, 2012)

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About this product

Product Information

A rapid, simple, accurate and economic High Performance Liquid Chromatographic analysis method has been developed for simultaneous estimation of Dorzolamide Hydrochloride (HCl) and Timolol Maleate in eye drop dosage forms is highly desirable to support formulation screening and quality control. The chromatography system used a reversed phase with C-18 column. The sample was analyzed using methanol: 1-octane sulphonic acid buffer, in the ratio of 55:45 as a mobile phase at a flow rate of 1.0 ml/min and detection with UV/Visible detector at two fixed wavelength (254.0 nm for Dorzolamide HCl and 295.0 nm for Timolol Maleate). The concentrations of these drugs were evaluated in marketed formulation by using simultaneous method. The present book describes the simultaneous estimation method of Dorzolamide Hydrochloride and Timolol Maleate in eye drop dosage form. The simultaneous estimation method given good recovery (accuracy), precision, linearity. Hence the method successfully used for quality control and routine analysis of drugs in eye drops dosage forms

Product Identifiers

Publisher
Lap Lambert Academic Publishing
ISBN-13
9783844314144
eBay Product ID (ePID)
117511726

Product Key Features

Author
Ravi Wanare
Publication Name
Estimation of Dorzolamide and Timolol in Eye Drops by a Rp-Hplc Method
Format
Paperback
Language
English
Subject
Medicine
Publication Year
2012
Type
Textbook
Number of Pages
92 Pages

Dimensions

Item Height
229mm
Item Width
152mm
Item Weight
145g

Additional Product Features

Title_Author
Ravi Wanare
Country/Region of Manufacture
Germany

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