Reviews"Excellent overview of the research that has, arguably, established genetic models as the dominant paradigm in the alcoholism field today."--Contemporary Psychology"Set[s] a high standard for thorough scholarly reviews of defined subject areas that will be invaluable for current researchers."--The Annals of Pharmacotherapy, "Excellent overview of the research that has, arguably, established genetic models as the dominant paradigm in the alcoholism field today."--Contemporary Psychology, "Set[s] a high standard for thorough scholarly reviews of defined subject areas that will be invaluable for current researchers."--The Annals of Pharmacotherapy
Dewey Edition20
TitleLeadingThe
Series Volume Number2
IllustratedYes
Dewey Decimal615.7/828
Table Of Content1. The Pharmacology of Alcohol DependenceI. General Pharmacology of Alcohol2. Pharmacokinetics of Ethanol: Absorption, Distribution and Elimination3. Metabolism of Ethanol, Acetaldehyde and Condensation Products4. Cross-Tolerance: Theoretical and Experimental IssuesII. Neuropharmacology of Alcohol6. Effects of Alcohol on Brain Circulation8. Alcohol, Alcoholism, and the Autonomic Nervous System: A Critical AccountIII. Neuropharmacology of Physical Dependence, Withdrawal, and Physiological Tolerance9. Effects of Alcohol on Neuronal Membranes10. Effect of Ethanol on Voltage-Gated Ion Channels11. Effect of Alcohol n Neurotransmitters and their Receptors and Enzymes12. Pharmacological Effects in the Development of Physiological Tolerance and Physical Dependence13. Neurobiological Substrates for the Anti-Anxiety Effects of Ethanol
SynopsisThis reference work covers the general pharmacology and neuropharmacology of alcohol as well as the pharmacological mechanisms underlying alcoholism., This is a comprehensive review of the pharmacological effects of alcohol and the mechanisms underlying the pathogenesis of alcoholism. The book draws on general pharmacology, neuropharmacology, and alcohol studies to explore its theme. The second volume in the ALCOHOL AND ALCOHOLISM series, it focuses on the pharmacologic mechanisms underlying the development of alcoholism. The first section on basic pharmacology is concerned with those aspects that are common to all of alcohol's effects. These include pharmacokinetics, general metabolism, and cross-tolerance. The second section on neuropharmacology describes the effects of alcohol on various brain functions, including circulation and metabolism. The third section provides an in-depth review of the neurobiology of physical dependence, withdrawal, and physiological tolerance. The book as a whole gives a comprehensive and authoritative picture of the complex pharmacologic actions of alcohol, particularly on the nervous system. For clinicians and researchers in the field of alcohol and alcoholism, it will serve as a fundamental reference.