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Introduction to Medicinal Chemistry by Graham L. Patrick (2013, Trade Paperback)

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Condition Notes: Used - Good: All pages and cover are intact including the dust cover, if applicable. Spine may show signs of wear. Pages may include limited notes and highlighting. Shrink wrap, dust covers, or boxed set case may be missing.

About this product

Product Identifiers

PublisherOxford University Press, Incorporated

ISBN-100199697396

ISBN-139780199697397

eBay Product ID (ePID)159815743

Product Key Features

Number of Pages816 Pages, 848 Pages

LanguageEnglish

Publication NameIntroduction to Medicinal Chemistry

Publication Year2013

SubjectChemistry / Clinical, Chemistry / General

TypeTextbook

Subject AreaScience

AuthorGraham L. Patrick

FormatTrade Paperback

Dimensions

Item Height1.5 in

Item Weight52.9 Oz

Item Length7.7 in

Item Width10.4 in

Additional Product Features

Edition Number5

Intended AudienceScholarly & Professional

LCCN2012-947637

Dewey Edition22

TitleLeadingAn

Reviews"It is difficult to improve on an already excellent book; however, this new edition provides yet more examples and very clear explanations to reinforce the fundamentals in Medicinal Chemistry. Patrick's style is easy to read and accessible for both undergraduate students and those studyingMedicinal Chemistry at a higher level." --Dr Zoe Waller, University of East Anglia, "Patrick's book is excellent. I always get good feedback from my students who find it informative, interesting, and readable." --Dr Alison Hill, University of Exeter, 'It is difficult to improve on an already excellent book; however, this new edition provides yet more examples and very clear explanations to reinforce the fundamentals in Medicinal Chemistry. Patrick's style is easy to read and accessible for both undergraduate students and those studying Medicinal Chemistry at a higher level.'Dr Zoë Waller, University of East Anglia'Patrick's book is excellent. I always get good feedback from my students who find it informative, interesting, and readable.'Dr Alison Hill, University of Exeter

IllustratedYes

Dewey Decimal615/.19

Table Of Content1. Drugs and drug targets - an overviewPART A Drug targets- structure and function2. Protein structure and function3. Enzymes: structure and function4. Receptors: structure and function5. Receptors and signal transduction6. Nucleic acids: structure and functionPART B Pharmacodynamics and pharmacokinetics7. Enzymes as drug targets8. Receptors as drug targets9. Nucleic acids as drug targets10. Miscellaneous drug targets11. Pharmacokinetics and related topicsCase study 1: StatinsPART C Drug discovery, design, and development12. Drug discovery: finding a lead13. Drug design: optimizing target interactions14. Drug design: optimizing access to the target15. Getting the drug to marketCase study 2: The design of ACE inhibitorsCase study 3: Artemisinin and related antimalarial drugsCase study 4 : The design of oxamniquinePART D Tools of the trade16. Combinatorial synthesis17. Computers in medicinal chemistry18. Quantitative structure-activity relationships (QSAR)Case study 5: De novo design of a thymidylate synthase inhibitorPART E Selected topics in medicinal chemistry19. Antibacterial agents20. Antiviral agents21. Anticancer agents22. Cholinergics, anticholinergics, and anticholinesterases23. Drugs acting on the adrenergic nervous system24. Opioid analgesics25. Antiulcer agentsCase study 6: Steroidal anti-inflammatory agentsCase Study 7: Design of a novel antidepressantAppendices

SynopsisAn Introduction to Medicinal Chemistry is the leading text for university courses on this subject. Renowned for being a textbook loved equally by both students and lecturers, it presents complete coverage in an accessible and engaging style. The text begins with the essential biochemistry on which an understanding of medicinal chemistry is built, introducing the structure and function of important drug targets. It then explores how drugs interact with the body and the consequences of those reactions. There is a section on general principles and strategies involved in discovering and designing new drugs, and another on useful 'tools of the trade'. The text ends with a contemporary look at specific topics within medicinal chemistry, for example, antiviral and anticancer agents; cholinergics and anticholinesterases; and antiulcer agents. Learning features throughout An Introduction to Medicinal Chemistry help to unlock this fascinating subject. A glossary helps to familiarise the language of medicinal chemistry. Boxes present in-depth material and explore how concepts are applied in practice. Key points summarise sections within chapters, providing a basis for revision, and questions at the end of chapters and on the accompanying Online Resource Centre allow the reader to test their understanding and develop molecular modelling skills. Online Resource Centre The Online Resource Centre features: For registered adopters of the book: DT Answers to end-of-chapter questions DT Figures from the book DT Power Point slides DT Test Bank questions For students: DT Multiple Choice Questions DT Web articles DT Molecular Modelling Exercises DT 3D Rotatable structures, An Introduction to Medicinal Chemistry is the leading text for university courses on this subject. Renowned for being a textbook loved equally by both students and lecturers, it presents complete coverage in an accessible and engaging style., An Introduction to Medicinal Chemistry is the leading text for university courses on this subject. Renowned for being a textbook loved equally by both students and lecturers, it presents complete coverage in an accessible and engaging style. The text begins with the essential biochemistry on which an understanding of medicinal chemistry is built, introducing the structure and function of important drug targets. It then explores how drugs interact with the body and the consequences of those reactions. There is a section on general principles and strategies involved in discovering and designing new drugs, and another on useful 'tools of the trade'. The text ends with a contemporary look at specific topics within medicinal chemistry, for example, antiviral and anticancer agents; cholinergics and anticholinesterases; and antiulcer agents.Learning features throughout An Introduction to Medicinal Chemistry help to unlock this fascinating subject. A glossary helps to familiarise the language of medicinal chemistry. Boxes present in-depth material and explore how concepts are applied in practice. Key points summarise sections within chapters, providing a basis for revision, and questions at the end of chapters and on the accompanying Online Resource Centre allow the reader to test their understanding and develop molecular modelling skills.Online Resource CentreThe Online Resource Centre features:For registered adopters of the book:· Answers to end-of-chapter questions· Figures from the book· Power Point slides· Test Bank questionsFor students:· Multiple Choice Questions· Web articles · Molecular Modelling Exercises· 3D Rotatable structures, An Introduction to Medicinal Chemistry is the leading text for university courses on this subject. Renowned for being a textbook loved equally by both students and lecturers, it presents complete coverage in an accessible and engaging style. The text begins with the essential biochemistry on which an understanding of medicinal chemistry is built, introducing the structure and function of important drug targets. It then explores how drugs interact with the body and the consequences of those reactions. There is a section on general principles and strategies involved in discovering and designing new drugs, and another on useful "tools of the trade". The text ends with a contemporary look at specific topics within medicinal chemistry, for example, antiviral and anticancer agents; cholinergics and anticholinesterases; and antiulcer agents.Learning features throughout help to unlock this fascinating subject. A glossary helps to familiarize the language of medicinal chemistry. Boxes present in-depth material and explore how concepts are applied in practice. Key points summarise sections within chapters, providing a basis for revision, and questions at the end of chapters and on the accompanying Online Resource Centre allow the reader to test their understanding and develop molecular modelling skills.

LC Classification NumberRS403