Calcitonin Gene-Related Peptide CGRP Mechanisms Focus on Migra

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Item specifics

Condition
Brand New: A new, unread, unused book in perfect condition with no missing or damaged pages. See the ...
Book title
Calcitonin Gene-Related Peptide CGRP Mechanisms Focus on Migra
ISBN
9783030214531
Subject Area
Medical
Publication Name
Calcitonin Gene-Related Peptide (Cgrp) Mechanisms : Focus on Migraine
Publisher
Springer International Publishing A&G
Item Length
9.3 in
Subject
Neurology, Pain Medicine, Pharmacology
Publication Year
2019
Series
Handbook of Experimental Pharmacology Ser.
Type
Textbook
Format
Hardcover
Language
English
Author
Pierangelo Geppetti
Item Weight
16.6 Oz
Item Width
6.1 in
Number of Pages
VII, 192 Pages
Category

About this product

Product Identifiers

Publisher
Springer International Publishing A&G
ISBN-10
3030214532
ISBN-13
9783030214531
eBay Product ID (ePID)
10038586894

Product Key Features

Number of Pages
VII, 192 Pages
Language
English
Publication Name
Calcitonin Gene-Related Peptide (Cgrp) Mechanisms : Focus on Migraine
Publication Year
2019
Subject
Neurology, Pain Medicine, Pharmacology
Type
Textbook
Author
Pierangelo Geppetti
Subject Area
Medical
Series
Handbook of Experimental Pharmacology Ser.
Format
Hardcover

Dimensions

Item Weight
16.6 Oz
Item Length
9.3 in
Item Width
6.1 in

Additional Product Features

Series Volume Number
255
Number of Volumes
1 vol.
Illustrated
Yes
Table Of Content
1. CGRP Discovery and Timeline.- 2. CGRP Receptor Biology: Is There More Than One Receptor?.- 3. The Structure of the CGRP and Related Receptors.- 4. CGRP Receptor Signalling Pathways.- 5. Pathways of CGRP Release from Primary Sensory Neurons.- 6. CGRP in Animal Models of Migraine.- 7. CGRP in Human Models of Migraine.- 8. Role of CGRP in Migraine.- 9. Understanding CGRP and Cardiovascular Risk.- 10. CGRP and Painful Pathologies other than Headache.- 11. Calcitonin Gene-Related Peptide Antagonists and Therapeutic Antibodies.
Synopsis
This book is designed to focus on the role of Calcitonin Gene-Related Peptide (CGRP) in health and disease. This peptide, originally discovered in the 1980s as a sensory neuropeptide with cardiovascular effects, is now known to play a distinct role in the pain processing of migraine. The various chapters address the origin, localization and function of CGRP and its receptor in the peripheral nervous system, in the cardiovascular system, and in other tissues and organs. Further attention is paid to the drug discovery pathway where recent findings show the beneficial effect of small molecule antagonists of the CGRP receptors for the relief of the migraine attack and of monoclonal antibodies against CGRP or the CGRP receptor for migraine prevention.
LC Classification Number
RM300-666

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