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Drug Metabolism and Pharmacokinetics Quick Guide

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Item specifics

Condition
Like New: A book that looks new but has been read. Cover has no visible wear, and the dust jacket ...
ISBN
9781441956286
Subject Area
Science, Medical
Publication Name
Drug Metabolism and Pharmacokinetics Quick Guide
Item Length
8 in
Publisher
Springer New York
Subject
Life Sciences / Biochemistry, Pharmacy, Pharmacology
Publication Year
2011
Type
Textbook
Format
Trade Paperback
Language
English
Author
Siamak Cyrus Khojasteh, Harvey Wong, Cornelis E. C. A. Hop
Item Width
5 in
Item Weight
16 Oz
Number of Pages
Xiii, 214 Pages

About this product

Product Information

Drug Metabolism and Pharmacokinetics Quick Guide covers a number of aspects of drug assessment at drug discovery and development stages, topics such as pharmacokinetics, absorption, metabolism, enzyme kinetics, drug transporters, drug interactions, drug-like properties, assays and in silico calculations. It covers key concepts, with useful tables on physiological parameters (eg. blood flow to organs in x-species, expression and localization of enzymes and transporters), chemical structure, nomenclature, and moieties leading to bioactivation (with examples). Overall it includes a number of key topics useful at the drug discovery stage, which would serve as a quick reference with several examples from the literature to illustrate the concept.

Product Identifiers

Publisher
Springer New York
ISBN-10
144195628x
ISBN-13
9781441956286
eBay Product ID (ePID)
7038864860

Product Key Features

Author
Siamak Cyrus Khojasteh, Harvey Wong, Cornelis E. C. A. Hop
Publication Name
Drug Metabolism and Pharmacokinetics Quick Guide
Format
Trade Paperback
Language
English
Subject
Life Sciences / Biochemistry, Pharmacy, Pharmacology
Publication Year
2011
Type
Textbook
Subject Area
Science, Medical
Number of Pages
Xiii, 214 Pages

Dimensions

Item Length
8 in
Item Width
5 in
Item Weight
16 Oz

Additional Product Features

Intended Audience
Scholarly & Professional
Number of Volumes
1 Vol.
Lc Classification Number
Rm300-666
Reviews
From the reviews: The authors have to be complimented with this comprehensive book of reference on various important topics in the field of pharmacokinetics and drug metabolism. It contains a large collection of figures and tables providing relevant and well-organized information. … In conclusion, this is a valuable reference for workers in the field of pharmacokinetics and drug metabolism, providing a storehouse of information in a comprehensive book. (Johannes H. Proost, International Journal of Clinical Pharmacology and Therapeutics, Vol. 50 (6), June, 2012) The authors intend the book to inform important decisions in a timely fashion 'for synthesis of superior compounds that have the potential for being a safe and effective drug'. The summary format was designed to be clear, concise and self-explanatory, so it could be used on a daily basis to inform those design decisions. It achieves this goal. It is intended for all drug-discovery scientists, and researchers in all disciplines will certainly find it useful. … In summary, this is a valuable little book. (Andy Davis, ChemMedChem, Vol. 7, 2012) This guide can be used on a day-to-day basis as a useful reference for almost anyone, including students first learning these concepts, as well as scientists in the pharmaceutical industry hoping to apply these principles in their research. … This is a nicely organized quick reference on basic concepts in pharmacokinetics and drug metabolism. It will be a useful addition to the libraries of a variety of readers, from students in the pharmaceutical sciences to accomplished researchers in drug development. (Melissa M. Ranieri, Doody's Book Reviews, December, 2011), From the reviews:The authors intend the book to inform important decisions in a timely fashion 'for synthesis of superior compounds that have the potential for being a safe and effective drug'. The summary format was designed to be clear, concise and self-explanatory, so it could be used on a daily basis to inform those design decisions. It achieves this goal. It is intended for all drug-discovery scientists, and researchers in all disciplines will certainly find it useful. … In summary, this is a valuable little book. (Andy Davis, ChemMedChem, Vol. 7, 2012)This guide can be used on a day-to-day basis as a useful reference for almost anyone, including students first learning these concepts, as well as scientists in the pharmaceutical industry hoping to apply these principles in their research. … This is a nicely organized quick reference on basic concepts in pharmacokinetics and drug metabolism. It will be a useful addition to the libraries of a variety of readers, from students in the pharmaceutical sciences to accomplished researchers in drug development. (Melissa M. Ranieri, Doody's Review Service, December, 2011), From the reviews: "The authors have to be complimented with this comprehensive book of reference on various important topics in the field of pharmacokinetics and drug metabolism. It contains a large collection of figures and tables providing relevant and well-organized information. ... In conclusion, this is a valuable reference for workers in the field of pharmacokinetics and drug metabolism, providing a storehouse of information in a comprehensive book." (Johannes H. Proost, International Journal of Clinical Pharmacology and Therapeutics, Vol. 50 (6), June, 2012) "The authors intend the book to inform important decisions in a timely fashion 'for synthesis of superior compounds that have the potential for being a safe and effective drug'. The summary format was designed to be clear, concise and self-explanatory, so it could be used on a daily basis to inform those design decisions. It achieves this goal. It is intended for all drug-discovery scientists, and researchers in all disciplines will certainly find it useful. ... In summary, this is a valuable little book." (Andy Davis, ChemMedChem, Vol. 7, 2012) "This guide can be used on a day-to-day basis as a useful reference for almost anyone, including students first learning these concepts, as well as scientists in the pharmaceutical industry hoping to apply these principles in their research. ... This is a nicely organized quick reference on basic concepts in pharmacokinetics and drug metabolism. It will be a useful addition to the libraries of a variety of readers, from students in the pharmaceutical sciences to accomplished researchers in drug development."­­­ (Melissa M. Ranieri, Doody's Book Reviews, December, 2011), From the reviews:This guide can be used on a day-to-day basis as a useful reference for almost anyone, including students first learning these concepts, as well as scientists in the pharmaceutical industry hoping to apply these principles in their research. … This is a nicely organized quick reference on basic concepts in pharmacokinetics and drug metabolism. It will be a useful addition to the libraries of a variety of readers, from students in the pharmaceutical sciences to accomplished researchers in drug development. (Melissa M. Ranieri, Doody's Review Service, December, 2011), From the reviews: "The authors have to be complimented with this comprehensive book of reference on various important topics in the field of pharmacokinetics and drug metabolism. It contains a large collection of figures and tables providing relevant and well-organized information. ... In conclusion, this is a valuable reference for workers in the field of pharmacokinetics and drug metabolism, providing a storehouse of information in a comprehensive book." (Johannes H. Proost, International Journal of Clinical Pharmacology and Therapeutics, Vol. 50 (6), June, 2012) "The authors intend the book to inform important decisions in a timely fashion 'for synthesis of superior compounds that have the potential for being a safe and effective drug'. The summary format was designed to be clear, concise and self-explanatory, so it could be used on a daily basis to inform those design decisions. It achieves this goal. It is intended for all drug-discovery scientists, and researchers in all disciplines will certainly find it useful. ... In summary, this is a valuable little book." (Andy Davis, ChemMedChem, Vol. 7, 2012) "This guide can be used on a day-to-day basis as a useful reference for almost anyone, including students first learning these concepts, as well as scientists in the pharmaceutical industry hoping to apply these principles in their research. ... This is a nicely organized quick reference on basic concepts in pharmacokinetics and drug metabolism. It will be a useful addition to the libraries of a variety of readers, from students in the pharmaceutical sciences to accomplished researchers in drug development." (Melissa M. Ranieri, Doody's Book Reviews, December, 2011)
Table of Content
Pharmacokinetics.- Drug Metabolizing Enzymes.- Oral Absorption.- Transporters.- Metabolism-Based Drug Interactions.- Biotransformation and Bioactivation.- Prediction of Human Pharmacokinetics.- Advances in Bioanalysis as it Relates to ADME.- ADME Properties and Their Dependence on Physicochemical Properties.- In Silico ADME Tools.- Approved Drugs.- Chemical Nomenclature.
Copyright Date
2011
Dewey Decimal
615.7
Dewey Edition
22
Illustrated
Yes

Item description from the seller

goodwillexpress

goodwillexpress

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