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Experimental Design for Biologists, Second Edition by David J. Glass - New
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Item specifics
- Condition
- Subject
- Life Sciences / Molecular Biology, Life Sciences / Biochemistry, Life Sciences / Developmental Biology, Life Sciences / Biology, Research & Methodology
- ISBN
- 9781621820413
- Subject Area
- Science
- Publication Name
- Experimental Design for Biologists, Second Edition
- Publisher
- Cold Spring Harbor Laboratory Press
- Item Length
- 10.4 in
- Publication Year
- 2014
- Type
- Textbook
- Format
- Hardcover
- Language
- English
- Item Height
- 0.9 in
- Features
- Revised
- Item Weight
- 28.9 Oz
- Item Width
- 8.1 in
- Number of Pages
- 294 Pages
About this product
Product Identifiers
Publisher
Cold Spring Harbor Laboratory Press
ISBN-10
1621820416
ISBN-13
9781621820413
eBay Product ID (ePID)
201638800
Product Key Features
Number of Pages
294 Pages
Publication Name
Experimental Design for Biologists, Second Edition
Language
English
Publication Year
2014
Subject
Life Sciences / Molecular Biology, Life Sciences / Biochemistry, Life Sciences / Developmental Biology, Life Sciences / Biology, Research & Methodology
Features
Revised
Type
Textbook
Subject Area
Science
Format
Hardcover
Dimensions
Item Height
0.9 in
Item Weight
28.9 Oz
Item Length
10.4 in
Item Width
8.1 in
Additional Product Features
Edition Number
2
Intended Audience
Scholarly & Professional
LCCN
2014-015021
Reviews
"[David Glass] has written an extraordinarily concise, highly instructive book based on a course he developed. It guides potential and practicing researchers through scientific epistemology and sound research design. The author uses extensive application examples, especially biological ones. Early chapters focus on philosophical constructs related to research issues, especially critical rationalism. The volume presents effective framing of both testing a hypothesis and a question/answer format." - Choice
Dewey Edition
23
Illustrated
Yes
Dewey Decimal
570.1/51
Edition Description
Revised edition
Table Of Content
Preface Section One: Philosophy of Experimentation 1. Why You Need to Read a Little Philosophy First: The Philosophy of Science Governs the Practice of Science 2. Defining Scientific Research 3. Why Do Science? What Is Science For? The Need for Inductive Reasoning 4. The First Step to Engaging in Scientific Research: Establishing Your Framework 5. A Short History of Philosophy Relevant to Scientific Method: How We Got to Where We Are Today and the Problem of Induction 6. The Sky Is Red Hypothesis: Examining the Hypothesis-Falsification Framework 7. The Hypothesis as a Framework for Scientific Projects: Is Critical Rationalism Critical Enough? 8. Scientific Settings in Which a Hypothesis-Falsification Framework Is Not Feasible 9. The Question and the Model: Forming an Inductive Framework for Scientific Projects (by Getting to Carnegie Hall) 10. Advantages to the Question/Model-Building Inductive Framework 11. A Biological Example of the Question/Model-Building Framework 12. Some Concluding Remarks on the Philosophy of Experimentation: Warnings and Exhortations Section Two: System Validation 13. The System 14. System Validation 15. Choice of a Model Organism or Technique: Validation Experiments 16. System Validation Requirements for Distinct Experimental Readouts 17. System Specificity: Specificity of Detection and Specificity of Perturbation 18. System Sensitivity: Minimizing Signal to Noise to Improve Sensitivity of Detection 19. System Stability 20. Determining Conditions to Measure Efficacy 21. System Validation: Determining Conditions to Measure Safety Section Three: The Experiment 22. Definition of the Experiment: The Framework for an Individual Experiment 23. The Negative Control: Distinct Types 24. The Requirement for the Positive Control 25. Method and Reagent Controls 26. Subject Controls 27. Assumption Controls 28. Experimentalist Controls: Establishing a Claim to an Objective Perspective 29. Biological Replicates, Technical Replicates, Experimental Repeats, Time Courses (Repeats over Time), and Dose Responses 30. Summary of the Components of the Individual Experiment Section Four: The Model 31. Building the Model: Representations of the Experimental Data 32. Data Filtration 33. Model Induction: Asking Follow-Up Questions and Finishing the Project by Writing the Manuscript 34. A Short Synopsis Section Five: Addendum Designing the Experimental Project: A Biological Example Index
Synopsis
The effective design and analysis of experiments in biology are critical to success, yet graduate students in biological and medical sciences typically receive very little formal training in these steps. With feedback from readers of the first edition, colleagues, and students taking the very popular experimental design courses taught by the author, this second edition of Experimental Design for Biologists retains the engaging writing style while organizing the book around the four elements of experimental design: the framework, the system, the experiment, and the model. The approach has been tested in the classroom, where the author has taught numerous graduate students, MD/PhD students, and postdoctoral fellows. The goal of every scientist is to discover something new and with the aid of Experimental Design for Biologists, this task is made a little easier. This handbook explains how to establish the framework for an experimental project, how to set up all of the components of an experimental system, design experiments within that system, determine and use the correct set of controls, and formulate models to test the veracity and resiliency of the data. This thoroughly updated edition of Experimental Design for Biologists is an essential source of theory and practical guidance for designing a research plan., Experimental Design for Biologists is a unique and successful handbook on the theory and practice of effective design of scientific experiments, based on a well-received course by the author. This second edition is entirely reorganized, rewritten, and includes new material and figures. The material is presented in seven parts: Philosophy of Scientific Experimentation, Mapping Out the Project, System Validation, Experimental Design, Examples, What Comes After, and Putting It All Together. Experimental Design for Biologists, Second Edition, is an essential source in designing a sound research plan, critical to the success of graduate students., "Experimental Design for Biologists is a unique and successful handbook on the theory and practice of effective design of scientific experiments, based on a well-received course by the author. This second edition is entirely reorganized, rewritten, and includes new material and figures. The material is presented in seven parts: Philosophy of Scientific Experimentation, Mapping Out the Project, System Validation, Experimental Design, Examples, What Comes After, and Putting It All Together. Experimental Design for Biologists, Second Edition, is an essential source in designing a sound research plan, critical to the success of graduate students"--, The effective design and analysis of experiments in biology are critical to success, yet graduate students in biological and medical sciences typically receive very little formal training in these steps. With feedback from readers of the first edition, colleagues, and students taking the very popular experimental design courses taught by the author, this second edition of Experimental Design for Biologists retains the engaging writing style while organizing the book around the four elements of experimental design: the framework, the system, the experiment, and the model. The approach has been tested in the classroom, where the author has taught numerous graduate students, MD/PhD students, and postdoctoral fellows. The goal of every scientist is to discover something new and with the aid of Experimental Design for Biologists , this task is made a little easier. This handbook explains how to establish the framework for an experimental project, how to set up all of the components of an experimental system, design experiments within that system, determine and use the correct set of controls, and formulate models to test the veracity and resiliency of the data. This thoroughly updated edition of Experimental Design for Biologists is an essential source of theory and practical guidance for designing a research plan.
LC Classification Number
QH323.5.G565 2014
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