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Bioisosteres in Medicinal Chemistry by Nathan Brown (English) Hardcover Book
AU $323.46
ApproximatelyUS $221.97
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eBay item number:155899565137
Item specifics
- Condition
- ISBN-13
- 9783527330157
- Book Title
- Bioisosteres in Medicinal Chemistry
- ISBN
- 9783527330157
- Subject Area
- Chemical Engineering
- Publication Name
- Bioisosteres in Medicinal Chemistry
- Publisher
- Wiley-Vch Verlag Gmbh
- Subject
- Medicine
- Publication Year
- 2012
- Type
- Textbook
- Format
- Hardcover
- Language
- English
- Item Height
- 258 mm
- Item Weight
- 628 g
- Item Width
- 170 mm
- Number of Pages
- 256 Pages
About this product
Product Information
Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development. The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered, while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization. The third part covers the four key methodologies for bioisostere identification and replacement: physicochemical properties, topology, shape, and overlays of protein-ligand crystal structures. In the final part, several real-world examples of bioisosterism in drug discovery projects are discussed. With its detailed descriptions of databases, methods and real-life case studies, this is tailor-made for busy industrial researchers with little time for reading, while remaining easily accessible to novice drug developers due to its systematic structure and introductory section.
Product Identifiers
Publisher
Wiley-Vch Verlag Gmbh
ISBN-13
9783527330157
eBay Product ID (ePID)
114420789
Product Key Features
Number of Pages
256 Pages
Language
English
Publication Name
Bioisosteres in Medicinal Chemistry
Publication Year
2012
Subject
Medicine
Type
Textbook
Subject Area
Chemical Engineering
Format
Hardcover
Dimensions
Item Height
258 mm
Item Weight
628 g
Item Width
170 mm
Additional Product Features
Editor
Nathan Brown
Country/Region of Manufacture
Germany
Series Title
Methods & Principles in Medicinal Chemistry
Item description from the seller
Business seller information
Value Added Tax Number:
- AU 82107909133
- GB 293967539
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- e***i (723)- Feedback left by buyer.Past 6 monthsVerified purchaseGreat product arrived in perfect condition as in the photos includes a good range of colours in the set for a full realisation of lots of skintone combinations. Was a great price very well packed very quick delivery good communication very happy with my purchase A + highly recommend this seller. 😀Model Colour - Face & Skin Tones 8 Colour Set (#145662750498)
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