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Methods and Principles in Medicinal Chemistry Ser.: Mass Spectrometry in...

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Item specifics

Condition
Like New: A book that looks new but has been read. Cover has no visible wear, and the dust jacket ...
Subject
Chemistry
ISBN
9783527314560
Publication Name
Mass Spectrometry in Medicinal Chemistry : Applications in Drug Discovery
Item Length
9.7in
Publisher
Wiley & Sons, Incorporated, John
Publication Year
2007
Series
Methods and Principles in Medicinal Chemistry Ser.
Type
Textbook
Format
Hardcover
Language
English
Item Height
1.1in
Author
Georg Höfner
Item Width
7in
Item Weight
34.8 Oz
Number of Pages
460 Pages

About this product

Product Information

This first overview of mass spectrometry-based pharmaceutical analysis is the key to improved high-throughput drug screening, rational drug design and analysis of multiple ligand-target interactions. The ready reference opens with a general introduction to the use of mass spectrometry in pharmaceutical screening, followed by a detailed description of recently developed analytical systems for use in the pharmaceutical laboratory. Applications range from simple binding assays to complex screens of biological activity and systems containing multiple targets or ligands -- all highly relevant techniques in the early stages in drug discovery, from target characterization to hit and lead finding.

Product Identifiers

Publisher
Wiley & Sons, Incorporated, John
ISBN-10
3527314563
ISBN-13
9783527314560
eBay Product ID (ePID)
57022099

Product Key Features

Author
Georg Höfner
Publication Name
Mass Spectrometry in Medicinal Chemistry : Applications in Drug Discovery
Format
Hardcover
Language
English
Publication Year
2007
Series
Methods and Principles in Medicinal Chemistry Ser.
Type
Textbook
Number of Pages
460 Pages

Dimensions

Item Length
9.7in
Item Height
1.1in
Item Width
7in
Item Weight
34.8 Oz

Additional Product Features

Series Volume Number
36
Lc Classification Number
Rs403
Reviews
"For those readers who are not familiar with mass spectrometry..." ( Lebensmittel & Biotechnologie , March 2007), "For those readers who are not familiar with mass spectrometry..." Lebensmittel & Biotechnologie (March 2007)
Table of Content
Mass Spectrometry in Bioanalysis - Methods, Principles and Instrumentation Drug Screening Using Gel Permeation Chromatography Spin Columns Coupled with ESI-MS ALIS: An Affinity Selection-Mass Spectrometry System for the Discovery and Characterization of Protein-Ligand Interactions Library Screening Using Ultrafiltration and Mass Spectrometry Continuous-Flow Systems for Ligand Binding and Enzyme Inhibition Assays Based on Mass Spectrometry Frontal Affinity Chromatography - Mass Spectrometry for Ligand Discovery and Characterization MS-Binding Assays - an Alternative to Radioligand Binding Laser Desorption Assays - MALDI-MS, DIOS-MS, and SAMDI-MS Tethering: Fragment-Based Drug Discovery by Mass Spectrometry Interrogation of Noncovalent Complexes by ESI-MS: A Powerful Platform for High Throughput Drug Discovery Quantification of Protein-Ligand Interactions in Solution by H/D Exchange (PLIMSTEX) Protein-Targeting Drug Discovery Guided by Hydrogen/Deuterium Exchange Mass Spectrometry (DXMS) Mass Spectrometry in Early Pharmacokinetic Investigations
Copyright Date
2007
Topic
Spectroscopy & Spectrum Analysis, Chemistry / Clinical, Chemistry / Industrial & Technical
Intended Audience
Scholarly & Professional
Illustrated
Yes
Genre
Science

Item description from the seller

shehuami

shehuami

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