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Clinical Pharmacokinetics and Pharmacodynamics : Concepts and Applications by Thomas N. Tozer and Malcolm Rowland (2010, Hardcover)
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Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications
- Buy It NowClinical Pharmacokinetics and Pharmacodynamics: Concepts and App
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About this product
Product Identifiers
PublisherLippincott Williams & Wilkins
ISBN-100781750091
ISBN-139780781750097
eBay Product ID (ePID)102883340
Product Key Features
Number of Pages864 Pages
Publication NameClinical Pharmacokinetics and Pharmacodynamics : concepts and Applications
LanguageEnglish
Publication Year2010
SubjectPharmacy, Internal Medicine, Pharmacology
FeaturesRevised
TypeTextbook
Subject AreaMedical
AuthorThomas N. Tozer, Malcolm Rowland
FormatHardcover
Dimensions
Item Weight63.3 Oz
Item Length10 in
Item Width7 in
Additional Product Features
Edition Number4
Intended AudienceScholarly & Professional
Dewey Edition22
Reviews-- "I believe this book is the best written text for bridging the gap between basic PK and clinical PK."
IllustratedYes
Dewey Decimal615.7
Table Of ContentPreface Definition of Symbols Non-Proprietary and Brand Names of Drugs in Text and Illustrations I. Basic Considerations 1. Therapeutic Relevance 2. Fundamental Concepts and Terminology II. Exposure and Response after a Single Dose 3. Kinetics Following an Intravenous Bolus Dose 4. Membranes and Distribution 5. Elimination 6. Kinetics Following an Extravascular Dose 7. Absorption 8. Response Following a Single Dose III. Therapeutic Regimens 9. Therapeutic Window 10. Constant-Rate Input 11. Multiple Dose Regimens IV. Individualization 12.Variability 13.Genetics 14. Age, Weight, and Gender 15. Disease 16. Nonlinearities 17. Drug Interactions 18. Initiating and Managing Therapy V. Supplemental Topics 19. Distribution Kinetics 20. Metabolites and Drug Response 21. New! Protein Drugs 22. New! Prediction and Refinement of Human Kinetics from In Vitro, Preclinical, and Early Clinical Data Appendices A. Assessment of AUC B. Ionization and the pH Partition Hypothesis C. Distribution of Drugs Extensively Bound to Plasma Proteins D. Plasma-to-Blood Concentration Ratio E. Well-stirred Model of Hepatic Clearance F. Absorption Kinetics G. Wagner-Nelson Method H. Mean Residence Time I. Amount of Drug in Body on Accumulation to Plateau J. Answers to Study Problems
Edition DescriptionRevised edition
SynopsisFormerly "Clinical Pharmacokinetics: Concepts and Clinical Applications, " this fully updated Fourth Edition has been retitled "Pharmacokinetics and Pharmacodynamics: Concepts and Clinical Applications" to reflect the increasing body of knowledge linking the two concepts that explain the relationship between drug administration and drug response. This revised edition also reflects the explosion in our understanding at the molecular and mechanistic levels of all the processes controlling the pharmacokinetics of drugs. The text is authored by two leading international experts on the clinical aspects of pharmacokinetics/pharmacodynamics and is widely considered one of the authoritative texts on the subject., Formerly Clinical Pharmacokinetics: Concepts and Applications, this fully updated Fourth Edition has been retitled Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications to reflect the increasing body of knowledge linking the two concepts that explain the relationship between drug administration and drug response. This revised edition also reflects the explosion in our understanding at the molecular and mechanistic levels of all the processes controlling the pharmacokinetics of drugs. The text is authored by two leading international experts on the clinical aspects of pharmacokinetics/pharmacodynamics and is widely considered one of the authoritative texts on the subject. A companion website includes the full text online, plus interactive simulations for student practice using different pharmacokinetic/pharmacodynamic models and parameters.
LC Classification NumberRM301.5.R68 2010
