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Iressa-A Boon to Colon Cancer by Saprativ Das (2011, Trade Paperback)

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Product Information

The epidermal growth factor receptor (EGFR) is under investigation as a therapeutic target for cancers. Colon cancer cell lines are variably dependent on autocrine stimulation of EGFR. This book therefore,examines the effects of a selective EGFR tyrosine kinase inhibitor, Gefitinib ( Iressa , ZD1839), on proliferation and survival of colon cancer cell lines whose autonomous proliferation is either EGFR ligand dependent or EGFR ligand independent. Using computational approach , different structural analogues were developed for Iressa, how it inhibits the epidermal growth factor kinase ; the studies include nature of the colon cancer and how Iressa work to stop cancer and also explains the ligand binding in EGFR kinase. The consequences help to understand the nature of epidermal growth factor receptor kinase and how to inhibit intra and extra cellular signal. The In-silico properties facilitate more efficient design of screening libraries and serves as a foundation for numerous ADME compound profiling and drug ability assessments along the drug discovery value chain. It also helps to stop the cancer development; a new guideline for the design of inhibitors.

Product Identifiers

Publisher
LAP Gmbh & Company KG
ISBN-10
3844311173
ISBN-13
9783844311174
eBay Product ID (ePID)
121023515

Product Key Features

Author
Saprativ Das
Publication Name
Iressa-A Boon to Colon Cancer
Format
Trade Paperback
Language
English
Publication Year
2011
Type
Textbook
Number of Pages
76 Pages

Dimensions

Item Length
9in
Item Height
0.2in
Item Width
6in
Item Weight
4.5 Oz

Additional Product Features

Topic
Anatomy, Life Sciences / Biology
Genre
Science, Medical

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Iressa-A Boon to Colon Cancer by Saprativ Das (2011, Trade Paperback)

About this product

Product Information

Product Identifiers

Product Key Features

Dimensions

Additional Product Features

Best Selling in Textbooks

Diagnostic and Statistical Manual of Mental Disorders DSM-5-TR by American Psychiatric Association (2022, Trade Paperback)

Leadership : Theory and Practice by Peter G. Northouse (2021, Trade Paperback, Revised edition)

Self Heal by Design : The Role of Micro-organisms for Health by Barbara O'Neill (2018, Trade Paperback)

Research Design : Qualitative, Quantitative, and Mixed Methods Approaches by J. David Creswell and John W. Creswell (2022, Trade Paperback)

Diagnostic and Statistical Manual of Mental Disorders : DSM-5-TR by American Psychiatric Association (2022, Hardcover)

Cognitive Behavior Therapy : Basics and Beyond by Judith S. Beck (2020, Hardcover)

Encyclopedia of Counseling : Master Review and Tutorial for the National Counselor Examination, State Counseling Exams, and the Counselor Preparation Comprehensive Examination by Howard Rosenthal (2017, Trade Paperback, Revised edition,New Edition)

Save on Textbooks

Diagnostic and Statistical Manual of Mental Disorders DSM-5-TR Brand new

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International Residential Code for One and Two-Family Dwellings 2021 free ship

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