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Signal Transduction by Bastien D. Gomperts, Ijsbrand M. Kramer, Peter E.R. Tatham (Paperback, 2003)

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About this product

Product Information

Signal Transduction now in paperback, is a text reference on cellular signalling processes. Starting with the basics, it explains how cells respond to external cues (hormones, cytokines, neurotransmitters, adhesion molecules, extracellular matrix, etc), and shows how these inputs are integrated and co-ordinated. The first half of the book provides the conceptual framework, explaining the formation and action of second messengers, particulary cyclic nucleotides and calcium, and the mediation of signal pathways by GTP-binding proteins. The remaining chapters deal with the formation of complex signalling cascades employed by cytokines and adhesion molecules, starting at the membrane and ending in the nucleus, there to regulate gene transcription. In this context, growth is an important potential outcome and this has relevance to the cellular transformations that underlie cancer. The book ends with a description at the molecular level of how signalling proteins interact with their environment and with each other through their structural domains. Each main topic is introduced with a historical essay, detailing the sources key observations and experiments that set the scence for recent and current work.

Product Identifiers

Publisher
Elsevier Science Publishing Co Inc
ISBN-13
9780122896323
eBay Product ID (ePID)
96583248

Product Key Features

Author
Bastien D. Gomperts, Ijsbrand M. Kramer, Peter E.R. Tatham
Publication Name
Signal Transduction
Format
Paperback
Language
English
Subject
Biology, Physics
Publication Year
2003
Type
Textbook
Number of Pages
440 Pages

Dimensions

Item Height
246mm
Item Width
189mm
Item Weight
1238g

Additional Product Features

Title_Author
Ijsbrand M. Kramer, Peter E.R. Tatham, Bastien D. Gomperts
Country/Region of Manufacture
United States

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