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Nephrotoxic Mechanisms of Drugs and Environmental Toxins by George A. Porter (Paperback, 2012)

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The majority of the offending toxicants to be reviewed in this volume were devel oped to help mankind, and it is only with prolonged or widespread application that their adverse effects have been recognized. Conversely, in the case of pre scrip tion drugs, there has been an attempt to identify the adverse effects in advance and incorporate these risks into the decision of approval for human consumption. Unfortunately, for those drugs in which recognized injury occurs only after prolonged use, such appraisals are made in retrospect. Despite this, most renal injury induced by drugs or toxicants can be either prevented by excluding drugs with unacceptable side effects or interrupted by eliminating the offending agent once damage is manifested. The fact that prevention, reversibility, or arrest of renal injury is possible provided a major impetus for this publication. Since no international registry for nephrotoxic injury exists, estimates of incidence must rely on less than ideal sources. Recently I, together with Dr. William Bennett, summarized a survey of the frequency of various categories of nephrologic disease (Porter and Bennett, 1981). Based on this survey, we projected that in nearly one of ten patients seeking nephrologic consultation a nephrotoxic etiology may be involved. Of cases of end-stage renal disease, between 3 and 4% are due to drug nephrotoxicity, according to recent published results(European Dialysis and Transplant Association, 1979). For acute renal failure, antibiotics and contrast agents persist as major offending agents, while for chronic renal failure, analgesics remain a worldwide problem.

Product Identifiers

Publisher
Springer-Verlag New York Inc.
ISBN-13
9781468442168
eBay Product ID (ePID)
208765947

Product Key Features

Author
George A. Porter
Publication Name
Nephrotoxic Mechanisms of Drugs and Environmental Toxins
Format
Paperback
Language
English
Subject
Chemistry
Publication Year
2012
Type
Textbook
Number of Pages
466 Pages

Dimensions

Item Height
254mm
Item Width
178mm
Item Weight
920g

Additional Product Features

Title_Author
George A. Porter
Country/Region of Manufacture
United States

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Nephrotoxic Mechanisms of Drugs and Environmental Toxins by George A. Porter (Paperback, 2012)

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Product Information

Product Identifiers

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Additional Product Features

Best Selling in Textbooks

Diagnostic and Statistical Manual of Mental Disorders DSM-5-TR by American Psychiatric Association (2022, Trade Paperback)

Leadership : Theory and Practice by Peter G. Northouse (2021, Trade Paperback, Revised edition)

Self Heal by Design : The Role of Micro-organisms for Health by Barbara O'Neill (2018, Trade Paperback)

Research Design : Qualitative, Quantitative, and Mixed Methods Approaches by J. David Creswell and John W. Creswell (2022, Trade Paperback)

Diagnostic and Statistical Manual of Mental Disorders : DSM-5-TR by American Psychiatric Association (2022, Hardcover)

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