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Virus Variability, Epidemiology and Control by M.H.V. Van Regenmortel, Edouard Kurstak, R.G. Marusyk, F.A. Murphy (Paperback, 2013)

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Virus Variability and Impact on Epidemiology and Control of Diseases E. Kurstak and A. Hossain I. INTRODUCTION An important number of virus infections and their epidemic developments demonstrate that ineffec tiveness of prevention measures is often due to the mutation rate and variability of viruses (Kurstak et al., 1984, 1987). The new human immunodeficiency retroviruses and old influenza viruses are only one among several examples of virus variation that prevent, or make very difficult. the production of reliable vaccines. It could be stated that the most important factor limiting the effectiveness of vaccines against virus infections is apparently virus variation. Not much is, how ever, known about the factors influencing and responsible for the dramatically diverse patterns of virus variability. II. MUTATION RATE AND VARIABILITY OF HUMAN AND ANIMAL VIRUSES Mutation is undoubtedly the primary source of variation, and several reports in the literature suggest that extreme variability of some viruses may be a consequence of an unusually high mutation rate (Holland et al., 1982; Domingo et al., 1985; Smith and Inglis, 1987). The mutation rate of a virus is defined as the probability that during a single replication of the virus genome a particular nucleotide position is altered through substitution, deletion, insertion. or recombination. Different techniques have been utilized to measure virus mutation rates, and these have been noted in the extent of application to different viruses.

Product Identifiers

Publisher
Springer-Verlag New York Inc.
ISBN-13
9781475792737
eBay Product ID (ePID)
189454868

Product Key Features

Author
M.H.V. Van Regenmortel, Edouard Kurstak, R.G. Marusyk, F.A. Murphy
Publication Name
Virus Variability, Epidemiology and Control
Format
Paperback
Language
English
Subject
Medicine, Zoology, Biology
Publication Year
2013
Type
Textbook
Number of Pages
368 Pages

Dimensions

Item Height
254mm
Item Width
178mm
Volume
2
Item Weight
736g

Additional Product Features

Series Title
Applied Virology Research
Country/Region of Manufacture
United States
Editor
Edouard Kurstak, M.H.V. Van Regenmortel, F.A. Murphy, R.G. Marusyk

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Virus Variability, Epidemiology and Control by M.H.V. Van Regenmortel, Edouard Kurstak, R.G. Marusyk, F.A. Murphy (Paperback, 2013)

About this product

Product Information

Product Identifiers

Product Key Features

Dimensions

Additional Product Features

Best Selling in Textbooks

Diagnostic and Statistical Manual of Mental Disorders DSM-5-TR by American Psychiatric Association (2022, Trade Paperback)

Leadership : Theory and Practice by Peter G. Northouse (2021, Trade Paperback, Revised edition)

Self Heal by Design : The Role of Micro-organisms for Health by Barbara O'Neill (2018, Trade Paperback)

Research Design : Qualitative, Quantitative, and Mixed Methods Approaches by J. David Creswell and John W. Creswell (2022, Trade Paperback)

Diagnostic and Statistical Manual of Mental Disorders : DSM-5-TR by American Psychiatric Association (2022, Hardcover)

Cognitive Behavior Therapy : Basics and Beyond by Judith S. Beck (2020, Hardcover)

Encyclopedia of Counseling : Master Review and Tutorial for the National Counselor Examination, State Counseling Exams, and the Counselor Preparation Comprehensive Examination by Howard Rosenthal (2017, Trade Paperback, Revised edition,New Edition)

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