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Cell Engineering Ser.: Apoptosis by Martin Fussenegger (2004, Hardcover)

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The suppression of apoptosis by the IGF system is critical for normal cell development, proliferation, differentiation and motility. Aberrations in IGF signalling mechanisms contribute to cell transformation, tumour progression and metastasis. Many questions remain to be answered as to how exactly the IGF system mediates its effects both in normal and tumour cells and how the IGF-1R interacting proteins and downstream signalling cascades are regulated. The importance of the IGF system is underscored by the significant interest in the development of anti-IGF therapies for IGF sensitive cancers. Future developments in cancer therapy are likely to focus on methods to target these therapies to diseased but not normal cells. 14. Acknowledgements We would like to thank Kurt Tidmore for preparing the illustrations. The Health Research Board of Ireland and Science Foundation Ireland are grateful acknowledged for funding. 15. References Adamo M., Roberts C. T., Jr. and LeRoith D. (1992) How distinct are the insulin and insul- like growth factor I signalling systems? Biofactors 3, 151-7. Adams T. E., Epa V. C., Garrett T. P. and Ward C. W. (2000) Structure and function of the type 1 insulin-like growth factor receptor. Cell Mol Life Sci 57, 1050-93. Adler V., Polotskaya A., Wagner F. and Kraft A. S. (1992) Affinity-purified c-Jun ami- terminal protein kinase requires serine/threonine phosphorylation for activity. J Biol Chem 267, 17001-5.

Product Identifiers

Publisher
Springer Netherlands
ISBN-10
1402022166
ISBN-13
9781402022166
eBay Product ID (ePID)
30783521

Product Key Features

Author
Martin Fussenegger
Publication Name
Apoptosis
Format
Hardcover
Language
English
Publication Year
2004
Series
Cell Engineering Ser.
Type
Textbook
Number of Pages
X, 334 Pages

Dimensions

Item Length
9.2in
Item Width
6.1in
Item Weight
51.9 Oz

Additional Product Features

Series Volume Number
4
Number of Volumes
1 Vol.
Lc Classification Number
Qh573-671
Table of Content
Caspase Regulation at the Molecular Level.- The Bcl-2 Family.- The IGF-1 Receptor in Cell Survival: Signalling and Regulation.- Apoptosis in Hepatocytes.- Programmed Cell Death in Plants During Development and Stress Responses.- A Systems View of Cell Death.- The Role of Caspases in Apoptosis and Their Inhibition in Mammalian Cell Culture.- Improvement of Industrial Cell Culture Processes by Caspase-9 Dominant Negative and Other Apoptotic Inhibitors.- Therapeutic Small Molecule Inhibitors of Bcl-2.- Apoptosis Control Based on Down-Regulating the Inhibitor-of-Apoptosis (IAP) Proteins: Xiap Antisense and Other Approaches.- Monitoring of Apoptosis.- Molecular Imaging of Programmed Cell Death; from Basic Mechanisms to Clinical Applications.
Copyright Date
2004
Topic
Life Sciences / Cell Biology, Life Sciences / Zoology / General, Life Sciences / Anatomy & Physiology (See Also Life Sciences / Human Anatomy & Physiology)
Lccn
2005-270785
Dewey Decimal
571.936
Intended Audience
Scholarly & Professional
Dewey Edition
22
Illustrated
Yes
Genre
Science

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Cell Engineering Ser.: Apoptosis by Martin Fussenegger (2004, Hardcover)

About this product

Product Information

Product Identifiers

Product Key Features

Dimensions

Additional Product Features

All listings for this product

item 1 Cell Engineering: Vol. 4: Apoptosis (2004, Hardcover) Free Shipping!

item 2 Cell Engineering: Apoptosis

item 3 Cell Engineering: Apoptosis by Mohamed Al-Rubeai (English) Hardcover Book

Best Selling in Textbooks

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Diagnostic and Statistical Manual of Mental Disorders DSM-5-TR by American Psychiatric Association (2022, Trade Paperback)

Self Heal by Design : The Role of Micro-organisms for Health by Barbara O'Neill (2018, Trade Paperback)

Leadership : Theory and Practice by Peter G. Northouse (2021, Trade Paperback, Revised edition)

Research Design : Qualitative, Quantitative, and Mixed Methods Approaches by J. David Creswell and John W. Creswell (2022, Trade Paperback)

Designing Data-Intensive Applications : The Big Ideas Behind Reliable, Scalable, and Maintainable Systems by Martin Kleppmann (2017, Trade Paperback)

PMBOK® Guide Ser.: Guide to the Project Management Body of Knowledge (PMBOK Guide) and the Standard for Project Management by Project Management Institute (2021, Trade Paperback)

Save on Textbooks

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