Organs and tissues that can tolerate little or no inflammation have developed multiple overlapping mechanisms of immune protection in the absence of inflammation. These areas have been designated immune-privileged sites by Peter Medawar and include the central nervous system, eye, reproductive tract, testis and possibly the liver. Mechanisms of immune homeostasis found in less immune-regulated organs are often evident in the immune privileged sites and vice versa. It is important that the non-inflammatory mechanisms that contribute to immune privilege allow host defense against infectious organisms. This volume highlights the mechanisms leading to immune privilege in tissues and organs, the deviation of immune responses and the modification of the behavior of the immune cells that manage to cross the blood barriers of tissues, in the context of infection.
Product Identifiers
Publisher
Springer Basel
ISBN-13
9783034807975
eBay Product ID (ePID)
209365796
Product Key Features
Author
Joan Stein-Streilein
Publication Name
Infection, Immune Homeostasis and Immune Privilege
Format
Paperback
Language
English
Subject
Medicine, Biology
Publication Year
2014
Type
Textbook
Number of Pages
156 Pages
Dimensions
Item Height
235mm
Item Width
155mm
Item Weight
267g
Additional Product Features
Series Title
Birkhauser Advances in Infectious Diseases
Country/Region of Manufacture
Switzerland
Editor
Joan Stein-Streilein
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