The present study is aimed to develop floating, pulsatile, multiparticulate drug delivery system intended for chronopharmacotherapy in arthritis. Cross-linked beads were prepared by using low methoxylated pectin, sodium alginate, low methoxylated pectin + Sodium alginate and low methoxylated pectin + deacetylated gellan by acid- base reaction during ionotropic gelation. Beads were dried in oven at 500 degree Cenntigrate for 4hr. Aceclofenac was used as a model drug for encapsulation. Drug loaded multiparticulates were subjected to various characterization and evaluation parameters like entrapment efficiency, buoyancy study, surface topography.
Product Identifiers
Publisher
LAP
ISBN-13
9783848437894
eBay Product ID (ePID)
115721403
Product Key Features
Author
Virendra Dhakar
Publication Name
Floating, Pulsatile, Multiparticulate Drug Delivery System
Format
Paperback
Language
English
Subject
Medicine
Publication Year
2012
Type
Textbook
Number of Pages
80 Pages
Dimensions
Item Height
229mm
Item Width
152mm
Item Weight
127g
Additional Product Features
Title_Author
Virendra Dhakar
Country/Region of Manufacture
Germany
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