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Conserved Signals of Ncrna Across 73 Genes Associated with Asd by Theodor Rais (Paperback / softback, 2009)

About this product

About this product

Product Information

The Autistic Spectrum Disorders (ASD), are kwn for their considerable heterogenic clinical presentation. Linkage studies have pointed toward very diverse areas of the geme related to the brain and associated with ASD. We hypothesized that small n-coding RNA (ncRNA), like miRNA, siRNA or orphan sRNAs, could be involved in the pathogenesis of ASD. A group of 73 genes associated with ASD were selected, proven through linkage studies, presence of biological markers (evidence of SNP's or haplotypes) or candidate genes association studies. A control group of 75 genes, which were predominantly expressed in n-brain tissues was selected. The results showed that the average number of conserved segments per intron in autism specific genes was 3.9, while it was 1.4 in the case of the genes minimally expressed in the brain. A n- parametric statistical test (Mann-Witney) showed a significant difference in degree of conservation between the two groups.

Product Identifiers

Brand
LAP
GTIN
9783838316765
UPC
9783838316765
eBay Product ID (ePID)
106575214

Product Key Features

Language
English
Publication Year
2009
Type
Textbook

Dimensions

Item Height
229 mm
Weight
104g
Depth
4 mm
Height
229mm
Width
152mm
Item Weight
104 g

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