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Advances in Biochemistry in Health and Disease Ser.: Cardiac Energy Metabolism in Health and Disease by Naranjan S. Dhalla (2014, Hardcover)

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The heart has a very high energy demand but very little energy reserves. In order to sustain contractile function, the heart has to continually produce a large amount of ATP. The heart utilizes free fatty acids mainly and carbohydrates to some extent as substrates for making energy and any change in this energy supply can seriously compromise cardiac function. It has emerged that alterations in cardiac energy metabolism are a major contributor to the development of a number of different forms of heart disease. It is also now known that optimizing energy metabolism in the heart is a viable and important approach to treating various forms of heart disease. Cardiac Energy Metabolism in Health and Disease describes the research advances that have been made in understanding what controls cardiac energy metabolism at molecular, transcriptional and physiological levels. It also describes how alterations in energy metabolism contribute to the development of heart dysfunction and how optimization of energy metabolism can be used to treat heart disease. The topics covered include a discussion of the effects of myocardial ischemia, diabetes, obesity, hypertrophy, heart failure, and genetic disorders of mitochondrial oxidative metabolism on cardiac energetics. The treatment of heart disease by optimizing energy metabolism is also discussed, which includes increasing overall energy production as well as increasing the efficiency of energy production and switching energy substrate preference of the heart. This book will be a valuable source of information to graduate students, postdoctoral fellows, and investigators in the field of experimental cardiology as well as biochemists, physiologists, pharmacologists, cardiologists, cardiovascular surgeons and other health professionals.

Product Identifiers

Publisher
Springer New York
ISBN-10
1493912267
ISBN-13
9781493912261
eBay Product ID (ePID)
201655732

Product Key Features

Author
Naranjan S. Dhalla
Publication Name
Cardiac Energy Metabolism in Health and Disease
Format
Hardcover
Language
English
Publication Year
2014
Series
Advances in Biochemistry in Health and Disease Ser.
Type
Textbook
Number of Pages
Xv, 295 Pages

Dimensions

Item Length
9.3in
Item Width
6.1in
Item Weight
23.2 Oz

Additional Product Features

Series Volume Number
11
Number of Volumes
1 Vol.
Lc Classification Number
Qd415-436
Table of Content
Part 1. Control of Energy Metabolism.- 1. A Primer on Carbohydrate Metabolism in the Heart.- 2. Lipoproteins: A Source of Cardiac Lipids.- 3. Role of Lipoprotein Lipase in Fatty Acid Delivery to the Heart.- 4. Control of Myocardial Fatty Acid Uptake.- 5. Cardiac Energy Metabolism in Heart Failure Associated with Obesity and Diabetes.- 6. Transcriptional Control of Mitochondrial Biogenesis and Maturation.- 7. Relationship between Substrate Metabolism and Cardiac Efficiency.- 8. Acetylation in the Control of Mitochondrial Metabolism and Integrity.- Part 2. Alteration in Energy Metabolism.- 9. Adrenergic Control of Cardiac Fatty Acid Oxidation in Diabetes.- 10. The Myocardial Creatine Kinase System in the Normal, Ischaemic and Failing Heart.- 11. Fuel Metabolism Plasticity in Pathological Cardiac Hypertrophy and Failure.- 12. Defects in Mitochondrial Oxidative Phosphorylation in Hearts Subjected to Ischemia-Reperfusion Injury.- 13. The Role of AMPK in the Control of Cardiac Hypertrophy.- 14. The Role of Incomplete Fatty Acid Oxidation in the Development of Cardiac Insulin Resistance.- Part 3. Optimization of Energy Metabolism.- 15. Metabolic Therapy for the Ischemic Heart.- 16. Inhibition of Fatty Acid Oxidation to Treat Heart Failure in Patients.- 17. Cardiac Metabolic Protection for the Newborn Heart.- 18. Targeting Transcriptional Control of Fatty Acid Oxidation to Treat Heart Disease.
Copyright Date
2014
Topic
Life Sciences / Biochemistry, Cardiology, Life Sciences / Biology, Research & Methodology
Dewey Decimal
612.173
Intended Audience
Scholarly & Professional
Dewey Edition
23
Illustrated
Yes
Genre
Science, Medical

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Advances in Biochemistry in Health and Disease Ser.: Cardiac Energy Metabolism in Health and Disease by Naranjan S. Dhalla (2014, Hardcover)

About this product

Product Information

Product Identifiers

Product Key Features

Dimensions

Additional Product Features

All listings for this product

item 1 Cardiac Energy Metabolism in Health and Disease, Hardcover by Lopaschuk, Gary...

item 2 Cardiac Energy Metabolism in Health and Disease, Hardcover by Lopaschuk, Gary...

item 3 Cardiac Energy Metabolism in Health and Disease by Gary D. Lopaschuk: New

item 4 Cardiac Energy Metabolism in Health and Disease by Gary D. Lopaschuk (English) H

item 5 Cardiac Energy Metabolism in Health and Disease (Hardback or Cased Book)

Best Selling in Textbooks

Diagnostic and Statistical Manual of Mental Disorders DSM-5-TR by American Psychiatric Association (2022, Trade Paperback)

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Designing Data-Intensive Applications : The Big Ideas Behind Reliable, Scalable, and Maintainable Systems by Martin Kleppmann (2017, Trade Paperback)

Cognitive Behavior Therapy : Basics and Beyond by Judith S. Beck (2020, Hardcover)

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