The whole area of growth hormone has been shrouded in controversy for some years. In the US, anxious parents apply pressure for their little ones to receive this elixir, regarless of whether there is a medical condition to treat. More recently, health care organisations have balked at the very high cost of growth hormone therapy while, with a greater consciousness of evidence-based medicine, there is also growing concerns about its efficay. There are now fears about the safety of long-term growth hormone administration with possible risks of increased cardiovascular disease and diabetes, although the latter seems to be a temporary phenomenon. At the clinical level there are also uncertainties about what optimum dosing schedules to use for both children and adults, and how to manage the transition from childhood to adult (when to stop giving hormone, how to follow up). Questions and Uncertainties about Growth Hormone Therapy will tackle theses issues and provide a timely and controversial review of these topics for endocrinologists and paediatricians.
Product Identifiers
Publisher
Wiley & Sons, Incorporated, John
ISBN-10
0632051647
ISBN-13
9780632051649
eBay Product ID (ePID)
764786
Product Key Features
Author
John P. Monson
Publication Name
Challenges in Growth Hormone Therapy
Format
Hardcover
Language
English
Series
Challenges in Ser.
Publication Year
1999
Type
Textbook
Number of Pages
320 Pages
Dimensions
Item Length
9.6in
Item Width
6.8in
Item Weight
26.7 Oz
Additional Product Features
Lc Classification Number
Rc658.7.C47 1999
Reviews
"This is an excellent book. It summarizes, in a concise yet reasonably comprehensive manner, the increasing literature on the theraputic use of growth hormone (GH) spawned by the recent availability of virtually unlimited quantities of GH obtained through recombinant DNA technology... the authors and the editor should be congratulated for assembling such a readable and yet comprehensive list". (Trends in Endocrinology & Metabolis Volume 11), "This is an excellent book. It summarizes, in a concise yet reasonably comprehensive manner, the increasing literature on the theraputic use of growth hormone (GH) spawned by the recent availability of virtually unlimited quantities of GH obtained through recombinant DNA technology... the authors and the editor should be congratulated for assembling such a readable and yet comprehensive list".(Trends in Endocrinology & Metabolis Volume 11)
Table of Content
1 GH replacement in children - what is the optimum dosing schedule?2 What is the current status of GH therapy in children with Turner's syndrome?3 Is there a role for GH therapy in Noonan's syndrome?4 Does GH therapy influence final height in skeletal dysplasia syndromes?5 Is there a role for GH therapy in short normal children?6 What is the role of GH therapy in children born small for gestational age?7 Is cardiovascular mortality increased in hypopituitary adults?8 How should we diagnose GH deficiency in hypopituitary adults?9 What is the impact of GH deficiency on bone density in childhood-onset and adult-onset GH deficiency, and how effective is GH replacement?10 Individual susceptibility and GH dosing regimen in adults11 What is the impact of GH deficiency and GH replacement on quality of life in childhood-onset and adult-onset GH deficiency?12 Is there an upper limit for GH replacement in hypopituitary adults?13 Is open-ended GH replacement a safe therapy?14 How should we evaluate GH treated patients at completion of linear growth?15 How should we transfer patients from paediatric to adult clinics?16 Is there a role for GH therapy in osteoporosis and in ageing?17 What is the current status of GH therapy in catabolic adults?18 Is GH therapy indicated in the metabolic syndrome?19 Does GH therapy have a role in management of cardiac failure?
Copyright Date
1999
Topic
Life Sciences / Biochemistry, Endocrinology & Metabolism