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About this product
Product Identifiers
PublisherFoster Academics
ISBN-101646466055
ISBN-139781646466054
eBay Product ID (ePID)17065850819
Product Key Features
Number of Pages240 Pages
Publication NameOsteoimmunology: Molecular Mechanisms and Clinical Applications
LanguageEnglish
Publication Year2023
SubjectImmunology, Osteopathy
TypeTextbook
Subject AreaMedical
AuthorMelonie Armstrong
FormatHardcover
Dimensions
Item Height0.6 in
Item Weight30 Oz
Item Length11 in
Item Width8.5 in
Additional Product Features
Intended AudienceTrade
SynopsisOsteoimmunology refers to an interdisciplinary research field that combines the field of immunology and osteology. It focuses on the potential treatments and mechanisms associated with bone related diseases, such as rheumatoid arthritis, periodontitis and osteoporosis that are caused by or linked with failure of the immune system. Receptor activator of nuclear factor kappaB ligand (RANKL) is the prime regulator of osteoclastogenesis. It is known to be responsible for the increased activation of osteoclasts, such as direct activation of T cells and indirect increase in the expression of RANKL, and consequently promoting osteoclastic activity. Osteoblasts have significance in the maintenance of the hematopoietic stem cell. Furthermore, they are also relevant in the development of lymphocytes, along with immune cell functions in the development of osteoclast and osteoblast. This book elucidates the concepts and innovative models around prospective developments with respect to osteoimmunology. Also included herein is a detailed explanation of the molecular mechanisms and clinical applications of this field. Those with an interest in this field would find this book helpful.