TubeTwist is a puzzle game in the vein of a classic "marble run" set, in which one builds an elaborate structure through which gravity pulls marbles from top to bottom. In the case of TubeTwist, marbles have been replaced by glowing balls of energy known as Macrotons. The renowned scientist who developed the Macrotons has disappeared through a portal created by her own invention, and gamers must solve puzzles to bring her back. Players complete contraptions using 30 different types of tubes, such as spirals, switches, and anti-gravity devices, all in an effort to get the Macrotons from their starting positions to a reactor tube where their energy can be extracted. The game features 100 puzzles, each with multiple solutions, and more puzzles can be downloaded from the Internet.