Reviews
"For the non-expert, this field can be more intimidating than a box of jumbled Christmas decorations. In Infectious Behavior: Brain-Immune Connections in Autism, Schizophrenia, and Depression , biologist Paul Patterson nimbly untangles the strings of lights." -- Virginia Hughes , Simons Foundation Autism Research Initiative, His title is a little daunting, but neurobiologist Patterson has succeeded in his aim of crafting an accessible, even fascinating, book about one of the hottest topics in mental health. In the long-running nature versus nurture argument, our era is all about nature. There is no one left -- no one with scientific credentials, at least -- who believes the way we nurture our offspring (cold mothers, distant fathers) creates autistic or schizophrenic children. But nature for too many people, experts and laypersons alike, means our genes alone. And they, Patterson shows, are not the whole story. He notes how the final health effects from the great flu pandemic of 1918, which killed more people than the Great War, played out very recently. Those who were in their mothers' wombs during the pandemic went on to a lifetime of health and socio-economic problems disproportionately worse than those of children born before or after: lower educational achievement and lower incomes, higher rates of diabetes and heart disease. Those outcomes are suggestive of the virus's effect on fetal brain development; the fact they often did not appear before adulthood supports the emerging hypothesis of the fetal origins of many adult diseases. Patterson describes the womb as a 'battlefield,' in which a fetus has to struggle to fend off rejection by the mother's immune system. Infection, which ramps up the immune response, can have devastating effects on fetal brains. The latest studies indicate that the risk of schizophrenia among the male offspring of women who come down with the flu during the first half of their pregnancies is three to seven times higher than usual. Patterson notes that common-sense ways to cut down on flu infection are widely known -- wash your hands and avoid airplane flights if at all possible -- but often ignored, even by pregnant women, because the stakes seem so small. He's done his best to correct that assumption., A chapter is devoted to an evidence-based review of the theory of a connection between vaccinations and autism. For this chapter alone, this book is worth a recommendation. This well-written book is good for anyone interested in behavior, disease, maternal-child health, and public health., "His title is a little daunting, but neurobiologist Patterson has succeeded in his aim of crafting an accessible, even fascinating, book about one of the hottest topics in mental health. In the long-running nature versus nurture argument, our era is all about nature. There is no one left -- no one with scientific credentials, at least -- who believes the way we nurture our offspring (cold mothers, distant fathers) creates autistic or schizophrenic children. But nature for too many people, experts and laypersons alike, means our genes alone. And they, Patterson shows, are not the whole story. He notes how the final health effects from the great flu pandemic of 1918, which killed more people than the Great War, played out very recently. Those who were in their mothers' wombs during the pandemic went on to a lifetime of health and socio-economic problems disproportionately worse than those of children born before or after: lower educational achievement and lower incomes, higher rates of diabetes and heart disease. Those outcomes are suggestive of the virus's effect on fetal brain development; the fact they often did not appear before adulthood supports the emerging hypothesis of the fetal origins of many adult diseases. Patterson describes the womb as a "battlefield," in which a fetus has to struggle to fend off rejection by the mother's immune system. Infection, which ramps up the immune response, can have devastating effects on fetal brains. The latest studies indicate that the risk of schizophrenia among the male offspring of women who come down with the flu during the first half of their pregnancies is three to seven times higher than usual. Patterson notes that common-sense ways to cut down on flu infection are widely known -- wash your hands and avoid airplane flights if at all possible -- but often ignored, even by pregnant women, because the stakes seem so small. He's done his best to correct that assumption." -- Macleans, Neurobiologist Paul Patterson, PhD, has produced a remarkably accessible and enjoyable book that intertwines history, case studies and laboratory science...It's an engaging and thought-provoking read for nonscientists and scientists alike., For the non-expert, this field can be more intimidating than a box of jumbledChristmas decorations. In Infectious Behavior: Brain-Immune Connections in Autism,Schizophrenia, and Depression , biologist Paul Patterson nimbly untangles the strings oflights., His title is a little daunting, but neurobiologist Patterson has succeeded in his aim of crafting an accessible, even fascinating, book about one of the hottest topics in mental health. In the long-running nature versus nurture argument, our era is all about nature. There is no one left--no one with scientific credentials, at least--who believes the way we nurture our offspring (cold mothers, distant fathers) creates autistic or schizophrenic children. But nature for too many people, experts and laypersons alike, means our genes alone. And they, Patterson shows, are not the whole story. He notes how the final health effects from the great flu pandemic of 1918, which killed more people than the Great War, played out very recently. Those who were in their mothers' wombs during the pandemic went on to a lifetime of health and socio-economic problems disproportionately worse than those of children born before or after: lower educational achievement and lower incomes, higher rates of diabetes and heart disease. Those outcomes are suggestive of the virus's effect on fetal brain development; the fact they often did not appear before adulthood supports the emerging hypothesis of the fetal origins of many adult diseases. Patterson describes the womb as a 'battlefield,' in which a fetus has to struggle to fend off rejection by the mother's immune system. Infection, which ramps up the immune response, can have devastating effects on fetal brains. The latest studies indicate that the risk of schizophrenia among the male offspring of women who come down with the flu during the first half of their pregnancies is three to seven times higher than usual. Patterson notes that common-sense ways to cut down on flu infection are widely known--wash your hands and avoid airplane flights if at all possible--but often ignored, even by pregnant women, because the stakes seem so small. He's done his best to correct that assumption., Neurobiologist Paul Patterson, PhD, has produced a remarkably accessible andenjoyable book that intertwines history, case studies and laboratory science.... It's an engagingand thought-provoking read for nonscientists and scientists alike., A chapter is devoted to an evidence-based review of the theory of a connectionbetween vaccinations and autism. For this chapter alone, this book is worth a recommendation. Thiswell-written book is good for anyone interested in behavior, disease, maternal-child health, andpublic health., The book is simultaneously accessible to the lay reader and insightful to the readerwith more expertise. It flows like a professor who rolls up his sleeves and delivers an engagingtalk to his audience without once looking at his slides. [It] is a well written, enjoyable read forany audience., "A chapter is devoted to an evidence-based review of the theory of a connection between vaccinations and autism. For this chapter alone, this book is worth a recommendation. This well-written book is good for anyone interested in behavior, disease, maternal-child health, and public health." -- Margaret Henderson , Library Journal, The book is simultaneously accessible to the lay reader and insightful to the reader with more expertise. It flows like a professor who rolls up his sleeves and delivers an engaging talk to his audience without once looking at his slides. [It] is a well written, enjoyable read for any audience., Patterson's book is so clear and compelling that it will appeal to clinicians awaiting novel disease models with new opportunities for prevention and cure, family members endlessly pondering the source of their loved one's ailment, and any reader who enjoys medical detective stories. A lucid synthesis of historical and current thinking about 'infectious' routes to mental illness., "Patterson's book is so clear and compelling that it will appeal to cliniciansawaiting novel disease models with new opportunities for prevention and cure, family membersendlessly pondering the source of their loved one's ailment, and any reader who enjoys medicaldetective stories. A lucid synthesis of historical and current thinking about "infectious" routes tomental illness." -- American Journal of Psychiatry, Neurobiologist Paul Patterson, PhD, has produced a remarkably accessible and enjoyable book that intertwines history, case studies and laboratory science.... It's an engaging and thought-provoking read for nonscientists and scientists alike., "the book is simultaneously accessible to the lay reader and insightful to the reader with more expertise. It flows like a professor who rolls up his sleeves and delivers an engaging talk to his audience without once looking at his slides. [It] is a well written, enjoyable read for any audience." -- Brain, Behavior, and Immunity, "Neurobiologist Paul Patterson, PhD, has produced a remarkably accessible and enjoyable book that intertwines history, case studies and laboratory science...It's an engaging and thought-provoking read for nonscientists and scientists alike." -- Autism Speaks blog, His title is a little daunting, but neurobiologist Patterson has succeeded in his aimof crafting an accessible, even fascinating, book about one of the hottest topics in mental health.In the long-running nature versus nurture argument, our era is all about nature. There is no oneleft -- no one with scientific credentials, at least -- who believes the way we nurture ouroffspring (cold mothers, distant fathers) creates autistic or schizophrenic children. But nature fortoo many people, experts and laypersons alike, means our genes alone. And they, Patterson shows, arenot the whole story. He notes how the final health effects from the great flu pandemic of 1918,which killed more people than the Great War, played out very recently. Those who were in theirmothers' wombs during the pandemic went on to a lifetime of health and socio-economic problemsdisproportionately worse than those of children born before or after: lower educational achievementand lower incomes, higher rates of diabetes and heart disease. Those outcomes are suggestive of thevirus's effect on fetal brain development; the fact they often did not appear before adulthoodsupports the emerging hypothesis of the fetal origins of many adult diseases. Patterson describesthe womb as a 'battlefield,' in which a fetus has to struggle to fend off rejection by the mother'simmune system. Infection, which ramps up the immune response, can have devastating effects on fetalbrains. The latest studies indicate that the risk of schizophrenia among the male offspring of womenwho come down with the flu during the first half of their pregnancies is three to seven times higherthan usual. Patterson notes that common-sense ways to cut down on flu infection are widely known --wash your hands and avoid airplane flights if at all possible -- but often ignored, even by pregnantwomen, because the stakes seem so small. He's done his best to correct that assumption., For the non-expert, this field can be more intimidating than a box of jumbled Christmas decorations. In Infectious Behavior: Brain-Immune Connections in Autism, Schizophrenia, and Depression , biologist Paul Patterson nimbly untangles the strings of lights., Patterson's book is so clear and compelling that it will appeal to cliniciansawaiting novel disease models with new opportunities for prevention and cure, family membersendlessly pondering the source of their loved one's ailment, and any reader who enjoys medicaldetective stories. A lucid synthesis of historical and current thinking about 'infectious' routes tomental illness.
