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Hemoglobin and Its Diseases by Alan N. Schechter (2013, Hardcover)

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Hemoglobin and Its Diseases by David Weatherall. Author David Weatherall. Title Hemoglobin and Its Diseases. Format Hardcover. Sports & Outdoors.

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Product Information

Hemoglobin is an iron-containing protein in red blood cells that transports oxygen to tissues throughout the body. The abundance, stability, and oxygen-carrying properties of hemoglobin can be altered by genetic mutations. More than one thousand hemoglobin disorders are known; hemoglobinopathies (e.g., sickle cell disease) and thalassemias are some of the most common human genetic diseases worldwide.Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine covers all aspects of hemoglobin and its diseases. Contributors examine the structure, expression, and evolution of the globin genes, the assembly of globin subunits into functional forms of hemoglobin, and the numerous variants that result from genetic alterations. The pathophysiological consequences of hemoglobin disorders (e.g., ineffective erythropoiesis and aberrant iron homeostasis), their clinical manifestations, and epidemiological trends are also described. This volume includes discussions of management and treatment strategies for hemoglobin disorders, such as transfusions, iron-chelating agents, gene therapy, and stem cell transplantation. It is an indispensable reference for biochemists, geneticists, cell and developmental biologists, physiologists, and all who are interested in reducing the medical burden of these common genetic diseases.

Product Identifiers

Publisher
Cold Spring Harbor Laboratory Press
ISBN-10
1936113457
ISBN-13
9781936113453
eBay Product ID (ePID)
144000756

Product Key Features

Author
Alan N. Schechter
Publication Name
Hemoglobin and Its Diseases
Format
Hardcover
Language
English
Publication Year
2013
Type
Textbook
Number of Pages
456 Pages

Dimensions

Item Length
10.3in
Item Height
1in
Item Width
7.3in
Item Weight
40.7 Oz

Additional Product Features

Lc Classification Number
Wh 120
Table of Content
Contents Preface Hemoglobin and its Disorders: 150 Years of Study David J. Weatherall, Alan N. Schechter, and David G. Nathan Erythopoiesis: Development and Differentiation Elaine Dzierzak and Sjaak Philipsen Erythropoietin H. Franklin Bunn Evolution of Hemoglobin and its Genes Ross C. Hardison Transcriptional Mechanisms Underlying Hemoglobin Synthesis Koichi R. Katsumura, Andrew W. DeVilbiss, Nathaniel J. Pope, Kirby D. Johnson, and Emery H. Bresnick The Switch from Fetal to Adult Hemoglobin Vijay G. Sankaran and Stuart H. Orkin Iron Metabolism: Interactions with Normal and Disordered Erythropoiesis Tomas Ganz and Elizabeta Nemeth Erythroid Heme Biosynthesis and its Disorders Harry A. Dailey and Peter N. Meissner Classification of the Disorders of Hemoglobin Bernard G. Forget and H. Franklin Bunn World Distribution, Population Genetics, and Health Burden of the Hemoglobinopathies Thomas N. Williams and David J. Weatherall The Molecular Basis of Beta Thalassemia Swee Lay Thein The Molecular Basis of Alpha Thalassemia Douglas R. Higgs Pathophysiology and Clinical Manifestations of the ? Thalassemias Arthur W. Nienhuis and David G. Nathan ?-Thalassemia Intermedia: A Clinical Perspective Khaled M. Musallam, Ali T. Taher, and Eliezer A. Rachmilewitz The Hemoglobin E Thalassemias Suthat Fucharoen and David J. Weatherall Clinical Manifestations of Alpha Thalassemia Elliott P. Vichinsky Alpha Thalassemia, Mental Retardation, and Myelodysplastic Syndrome Richard J. Gibbons Management of the Thalassemias Nancy F. Olivieri and Gary M. Brittenham The Prevention of Thalassemia Antonio Cao and Yuet Wai Kan The Natural History of Sickle Cell Disease Graham R. Serjeant The Search for Genetic Modifiers of Disease Severity in the ?-Hemoglobinopathies Guillaume Lettre Current Management of Sickle Cell Anemia Patrick T. McGann, Alecia Nero, and Russell E. Ware Hematopoietic Stem Cell Transplantation in Thalassemia and Sickle Cell Anemia Guido Lucarelli, Antonella Isgrò, Pietro Sodani, and Javid Gaziev Development of Gene Therapy for Thalassemia Arthur W. Nienhuis and Derek A. Persons Pluripotent Stem Cells in Research and Treatment of Hemoglobinopathies Natasha Arora and George Q. Daley Hemoglobin Variants: Biochemical Properties and Clinical Correlates Christopher S. Thom, Claire F. Dickson, David A. Gell, and Mitchell J. Weiss Cell Free Hemoglobin and its Scavenger Proteins: New Disease Models Leading the Way to Targeted Therapies Dominik J. Schaer and Paul W. Buehler Iron Deficiency Anemia: A Common and Curable Disease Jeffery L. Miller Index
Copyright Date
2012
Topic
Hematology, Life Sciences / General
Lccn
2012-027357
Dewey Decimal
612.1/111
Dewey Edition
23
Illustrated
Yes
Genre
Science, Medical

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Hemoglobin and Its Diseases by Alan N. Schechter (2013, Hardcover)

About this product

Product Information

Product Identifiers

Product Key Features

Dimensions

Additional Product Features

All listings for this product

item 1 Hemoglobin and Its Diseases by David Weatherall (English) Hardcover Book

item 2 Hemoglobin and Its Diseases by David Weatherall: New

Best Selling in Textbooks

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PMBOK® Guide Ser.: Guide to the Project Management Body of Knowledge (PMBOK Guide) and the Standard for Project Management by Project Management Institute (2021, Trade Paperback)

Diagnostic and Statistical Manual of Mental Disorders DSM-5-TR by American Psychiatric Association (2022, Trade Paperback)

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PMBOK A Guide to the Project Management Body of Knowledge 7th edition (Pb) 📋

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